北极环境对人类脑血流的影响

Feifeng Liu, Tianheng Zheng, Jian Chen, Huazheng Liang, Gang Li, Junjie Hao
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摘要

背景:北极环境是一种极端的生活条件,对生命有重大影响。但有关北极高纬度、低温环境下人体脑血流(CBF)变化的研究仍然缺乏。研究方法招募乘坐 "雪龙 2 号 "破冰船前往北极的中国第 12 次国家北极科考队队员。分别在航行初期(低纬度、高温度,LLHT)和北极科学考察期间(高纬度、低温度,HLLT)进行经颅彩色多普勒(TCD)检查。比较了脑动脉的频谱模式和参数。结果:在 16 名健康人中,13 人完成了两次 TCD 检查。他们的左侧大脑中动脉平均速度(Vm)(63.5 厘米/秒 HLLT 对 68.4 厘米/秒 LLHT;P=0.028)和收缩峰值速度(PSV)(94.6 厘米/秒 HLLT 对 107.0 厘米/秒 LLHT;P=0.038)明显较低。与 LLHT 相比,HLLT 环境下左侧大脑中动脉(LMCA)的搏动指数(PI)更高(0.83 HLLT vs. 077 LLHT; P=0.011)。结论在北极较高纬度和较低温度的环境中,人体 CBF 可能会发生变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of Arctic environments on human cerebral blood flow
Background: The Arctic environment represents an extreme living condition that has significant impact on life. But research on alterations of human cerebral blood flow (CBF) in a high-latitude and low-temperature environment in the Arctic is still lacking. Methods: Members of the 12th Chinese National Arctic Research Expedition team who took the icebreaker R/V Xuelong 2 to the Arctic were recruited. Transcranial colour doppler (TCD) examination was performed at the beginning of the voyage (lower latitude and higher temperature, LLHT) and during the Arctic scientific expedition period (higher latitude and lower temperature, HLLT) respectively. The spectral pattern and parameters of cerebral arteries were compared. Results: Among 16 healthy individuals, 13 completed the TCD examination twice. They had a significantly lower mean velocity (Vm) (63.5 cm/s HLLT vs. 68.4cm/s LLHT; P=0.028) and peak systolic velocity (PSV) (94.6cm/s HLLT vs. 107.0cm/s LLHT; P=0.038) of the left middle cerebral artery (LMCA) and higher pulsatility index (PI) of the right middle cerebral artery (RMCA) (0.83 HLLT vs. 077 LLHT; P=0.011) in the HLLT environment compared to the LLHT one. Conclusions: Changes in human CBF may occur in higher-latitude and lower-temperature environments in the Arctic.
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