明尼苏达大学在遗传学和临床药物基因组学方面达到新的 AACP 能力要求。

Innovations in pharmacy Pub Date : 2023-11-20 eCollection Date: 2023-01-01 DOI:10.24926/iip.v14i4.5142
Jacob T Brown, Lindsay A Sorge, William S Oetting, Pamala A Jacobson, Chrystian Pereira
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摘要

目的:药物基因组学 (PGx) 越来越多地被用于为患者提供个性化治疗。医疗保健专业人员,尤其是药剂师,需要了解基因变异如何影响药物的疗效和毒性。由于 PGx 相关信息的广泛性和复杂性,确定药学课程中应包含哪些信息以及如何最好地教育学生一直是个难题。方法:明尼苏达大学药学院最近开始将美国药学院协会 (AACP) 药物基因组学兴趣小组 (PGx-SIG) 的 PGx 扩展能力纳入课程。我们针对 PGx 内容对课程进行了评估,确定了目前的教学内容,并找出了教育差距。结果:对我们的药学博士课程进行审查后发现,虽然在必修课程中教授的 PGx 内容并不一致,有些课程甚至没有教授 PGx 内容,但 PGx 内容还是非常丰富的。我们修订了现有课程的内容,纳入了符合 PGx-SIG 推荐能力的大部分内容。结论:我们对 PGx 对个体化医疗的影响的理解正在并将发生重大变化。随着我们认识的加深,药学课程中有关 PGx 的信息也需要跟上这些变化的步伐。我们明尼苏达大学已经开始了这一进程,对 PGx 相关信息进行了全面审查,并对药学课程进行了适当修订。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Meeting the New AACP Competencies in Genetics and Clinical Pharmacogenomics at the University of Minnesota.

Objective: Pharmacogenomics (PGx) is increasingly being used for creating individualized treatments for patient care. Healthcare professionals, especially pharmacists, need to understand how genetic variation impacts the efficacy and toxicity of medications. Due to the breadth and complexity of PGx-related information, it has been challenging to determine what information should be included in pharmacy curricula and how best to educate students. Methods: The University of Minnesota College of Pharmacy recently began the process of incorporating into the curriculum expanded competencies for PGx from the American Association of Colleges of Pharmacy (AACP) Pharmacogenomics Special Interest Group (PGx-SIG). We evaluated our curriculum for PGx content, determined what was currently being taught and identified educational gaps. Results: A review of our Doctor of Pharmacy curriculum showed substantial PGx content, although it was inconsistently taught throughout the required courses and in some courses absent. We revised the content of existing courses incorporating content that meet most of the PGx-SIG recommended competencies. Conclusion: There are and will be major changes in our understanding of the influences of PGx on individualized medical treatment. As our understanding grows, information on PGx in pharmacy curriculums will need to keep pace with these changes. We have begun this process at the University of Minnesota by doing a full review of PGx related information and making appropriate revisions in the pharmacy curriculum.

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