用于小儿心脏手术后阿片类药物稀释的多模式疼痛治疗的脊髓后凸肌阻滞。

IF 4.9 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Nathalie Roy MD , M. Fernanda Parra MD , Morgan L. Brown MD, PhD , Lynn A. Sleeper ScD , Joe Kossowsky PhD , Andreas M. Baumer MSc , Sarah E. Blitz BS, BA , Jocelyn M. Booth RN , Connor E. Higgins BS , Viviane G. Nasr MD, MPH , Pedro J. del Nido MD , Roland Brusseau MD
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引用次数: 0

摘要

目的:建议采用外周区域麻醉来促进术后恢复。我们试图评估:双侧连续竖脊肌平面阻滞(B-ESpB)用于术后镇痛的疗效以及对接受心脏手术的儿童术后恢复的影响:方法:在心脏外科术后恢复强化项目(ERAS)中接受心脏手术的 2 至 17 岁患者被前瞻性地纳入到该项目中,在手术结束时接受 B-ESpB,术后通过导管持续输注。参与者在出院前一直佩戴活动监测器。B-ESpB 患者与 ERAS 项目中的对照组患者进行了回顾性配对。使用精确条件逻辑回归和广义线性建模对匹配群组的结果进行比较:40名接受BESB治疗的患者与78名对照组患者进行了配对。B-ESpB 或输液没有引起重大并发症,手术室时间中位数延长了 31 分钟。在阻滞输液期间,B-ESpB 患者在 24 小时(0.60±0.06 vs 0.78±0.04 mg/kg,p=0.02)和 48 小时(1.13±0.08 vs 1.35±0.06 mg/kg,p=0.04)时接受的阿片类药物口服吗啡当量(OME)分别少于对照组。两组患者每12小时的疼痛评分中位数均较低。结论:B-ESpB在早期活动、住院时间和并发症方面没有差异:结论:B-ESpB对接受心脏手术的儿童是安全的。如果在 ERAS 计划中将 B-ESpB 作为多模式止痛策略的一部分来实施,那么接受 B-ESpB 的儿童患者可以获得良好的疼痛控制效果,并且在最初的 48 小时内需要的阿片类药物较少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Erector spinae plane blocks for opioid-sparing multimodal pain management after pediatric cardiac surgery

Objective

Peripheral regional anesthesia is proposed to enhance recovery. We sought to evaluate the efficacy of bilateral continuous erector spinae plane blocks (B-ESpB) for postoperative analgesia and the impact on recovery in children undergoing cardiac surgery.

Methods

Patients aged 2 through 17 years undergoing cardiac surgery in the enhanced recovery after cardiac surgery program were prospectively enrolled to receive B-ESpB at the end of the procedure, with continuous infusions via catheters postoperatively. Participants wore an activity monitor until discharge. B-ESpB patients were retrospectively matched with control patients in the enhanced recovery after cardiac surgery program. Outcomes of the matched clusters were compared using exact conditional logistic regression and generalized linear modeling.

Results

Forty patients receiving B-ESpB were matched to 78 controls. There were no major complications from the B-ESpB or infusions, and operating room time was longer by a median of 31 minutes. While blocks were infusing, patients with B-ESpB received fewer opioids in oral morphine equivalents than controls at 24 hours (0.60 ± 0.06 vs 0.78 ± 0.04 mg/kg; P = .02) and 48 hours (1.13 ± 0.08 vs 1.35 ± 0.06 mg/kg; P = .04), respectively. Both groups had low median pain scores per 12-hour period. There was no difference in early mobilization, length of stay, or complications.

Conclusions

B-ESpBs are safe in children undergoing cardiac surgery. When performed as part of a multimodal pain strategy in an enhanced recovery after cardiac surgery program, pediatric patients with B-ESpB experience good pain control and require fewer opioids in the first 48 hours.
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来源期刊
CiteScore
11.20
自引率
10.00%
发文量
1079
审稿时长
68 days
期刊介绍: The Journal of Thoracic and Cardiovascular Surgery presents original, peer-reviewed articles on diseases of the heart, great vessels, lungs and thorax with emphasis on surgical interventions. An official publication of The American Association for Thoracic Surgery and The Western Thoracic Surgical Association, the Journal focuses on techniques and developments in acquired cardiac surgery, congenital cardiac repair, thoracic procedures, heart and lung transplantation, mechanical circulatory support and other procedures.
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