用于喹喔啉衍生物合成的 Β 环糊精重点分析

IF 1.7 3区化学 Q3 CHEMISTRY, ORGANIC

Current Organic Chemistry Pub Date : 2024-03-12 DOI:10.2174/0113852728295463240216074814

Hena Khatoon, Emilia Abdul Malek

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引用次数: 0

摘要

:环糊精（CD）是一种环状低聚糖，广泛应用于超分子化学领域。例如，它们可用于将药物等挥发性化合物封装在其疏水空腔中。这种封装可降低化合物的挥发性，并有助于保持其所需的特性。由于环糊精具有非凡的特性，在许多有机合成过程中被用作催化剂。有机化学家的一个固有目标是通过减少化学废物和能源消耗来优化有机合成的功效。因此，利用水作为绿色溶剂既经济又环保，而且安全可靠。将水与可回收催化剂结合使用似乎是超分子催化的最有效方法。因此，我们在本综述中重点探讨了如何利用水作为溶剂，环糊精作为聚合物催化剂，以环保和可持续的方式生产喹喔啉衍生物。

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A Focussed Analysis of Β-cyclodextrins for Quinoxaline Derivatives Synthesis

: Cyclodextrins (CDs), which are a type of cyclic oligosaccharides, are widely used in supramolecular chemistry. For example, they can be used to encapsulate volatile compounds, such as drugs, within their hydrophobic cavity. This encapsulation reduces the volatility of the compounds and helps to retain their desired properties. Due to its extraordinary properties, cyclodextrins have been utilized as catalysts in numerous organic synthesis processes. An intrinsic objective of organic chemists is to optimize the efficacy of organic synthesis through the mitigation of chemical waste and energy expenditure. Utilizing water as a green solvent is, therefore, economical, environmentally sustainable, and secure. It appears that employing water in conjunction with a recyclable catalyst is the most effective method for supramolecular catalysis. As a consequence, we focused this review on the use of water as a solvent and cyclodextrin as a polymer catalyst to produce quinoxaline derivatives in an environmentally friendly and sustainable manner

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来源期刊

Current Organic Chemistry 化学-有机化学

CiteScore

3.70

自引率

7.70%

发文量

审稿时长

1 months

期刊介绍： Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.