维生素 D 对妊娠和妊娠结局的影响:当前知识与未来展望。

IF 2 4区 医学 Q2 OBSTETRICS & GYNECOLOGY
Gynecologic and Obstetric Investigation Pub Date : 2024-01-01 Epub Date: 2024-03-08 DOI:10.1159/000538085
Zhanar Kurmangali, Bibigul Abdykalykova, Aimen Kurmangali, Danat Zhantagulov, Milan Terzic
{"title":"维生素 D 对妊娠和妊娠结局的影响:当前知识与未来展望。","authors":"Zhanar Kurmangali, Bibigul Abdykalykova, Aimen Kurmangali, Danat Zhantagulov, Milan Terzic","doi":"10.1159/000538085","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of the research was to explore the relationship between pathology and pregnancy outcomes with serum 25-hydroxycholecalciferol levels and vitamin D supplementation.</p><p><strong>Methods: </strong>A literature search was performed for systematic literature reviews published between January 2018 and February 2023. Forty-two publications were selected for further analysis.</p><p><strong>Results: </strong>This study demonstrates that elevated maternal serum 25(OH)D levels are associated with a decreased risk of preterm labour and various pregnancy-related health issues, highlighting the protective benefits of adequate vitamin D during pregnancy.</p><p><strong>Conclusion: </strong>Vitamin D supplementation during pregnancy at a dose of 2,000 IU or higher is preventive for pre-eclampsia, insulin resistance, and the development of bronchial asthma in early childhood. Vitamin D screening is indicated for all pregnant women. Dosages of vitamin D preparations should be determined individually, considering laboratory tests and risk factors.</p>","PeriodicalId":12952,"journal":{"name":"Gynecologic and Obstetric Investigation","volume":" ","pages":"261-266"},"PeriodicalIF":2.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Influence of Vitamin D on Pregnancy and Outcomes: Current Knowledge and Future Perspectives.\",\"authors\":\"Zhanar Kurmangali, Bibigul Abdykalykova, Aimen Kurmangali, Danat Zhantagulov, Milan Terzic\",\"doi\":\"10.1159/000538085\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The purpose of the research was to explore the relationship between pathology and pregnancy outcomes with serum 25-hydroxycholecalciferol levels and vitamin D supplementation.</p><p><strong>Methods: </strong>A literature search was performed for systematic literature reviews published between January 2018 and February 2023. Forty-two publications were selected for further analysis.</p><p><strong>Results: </strong>This study demonstrates that elevated maternal serum 25(OH)D levels are associated with a decreased risk of preterm labour and various pregnancy-related health issues, highlighting the protective benefits of adequate vitamin D during pregnancy.</p><p><strong>Conclusion: </strong>Vitamin D supplementation during pregnancy at a dose of 2,000 IU or higher is preventive for pre-eclampsia, insulin resistance, and the development of bronchial asthma in early childhood. Vitamin D screening is indicated for all pregnant women. Dosages of vitamin D preparations should be determined individually, considering laboratory tests and risk factors.</p>\",\"PeriodicalId\":12952,\"journal\":{\"name\":\"Gynecologic and Obstetric Investigation\",\"volume\":\" \",\"pages\":\"261-266\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gynecologic and Obstetric Investigation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000538085\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/3/8 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gynecologic and Obstetric Investigation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000538085","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/3/8 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

维生素 D 缺乏会增加不良妊娠结局的风险。维生素 D 缺乏症在全球的高发率要求对科学出版物进行分析,以便为孕妇维生素 D 缺乏症的预防、管理和治疗提出建议。研究的目的是探讨病理学和妊娠结局与血清 25- 羟基胆钙化醇水平和维生素 D 补充剂之间的关系。研究人员对2018年1月至2023年2月期间发表的带有荟萃分析的系统性文献综述进行了文献检索。选取了 42 篇文献进行进一步分析。24项荟萃分析评估了血清25-羟基胆钙化醇水平与妊娠过程和结果之间的关系。18 项荟萃分析侧重于维生素 D 制剂对产科和儿科病理发展的预防作用。研究发现,缺乏维生素 D 会增加自然流产(OR=1.6 (1.11; 2.3))、早产(OR=1.33 (1.15; 1.54)),尤其是多胎妊娠(OR=2.59 (1.35; 4.95))、先兆子痫(OR=1.33 (1.15; 1.54))的概率。95)、先兆子痫(OR=1.58(1.39-1.79))、妊娠贫血(OR=1.61(1.41;1.83))、产后抑郁(OR=3.67(1.72;7.85))、幼儿期自闭症谱系障碍(OR=1.54(1.12;2.1))。高维生素 D 水平可降低妊娠糖尿病(RR=0.87 (0.79; 0.97))和低出生体重(RR=0.65 (0.48; 0.86))的风险。孕期 25- 羟维生素 D 的目标水平是血清浓度超过 30 毫克/毫升。孕期补充 2000 IU 或更高剂量的维生素 D 可预防先兆子痫、胰岛素抵抗和幼儿期支气管哮喘的发生。维生素 D 筛查适用于所有孕妇。维生素 D 制剂的剂量应根据实验室检测结果和风险因素单独确定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Influence of Vitamin D on Pregnancy and Outcomes: Current Knowledge and Future Perspectives.

Introduction: The purpose of the research was to explore the relationship between pathology and pregnancy outcomes with serum 25-hydroxycholecalciferol levels and vitamin D supplementation.

Methods: A literature search was performed for systematic literature reviews published between January 2018 and February 2023. Forty-two publications were selected for further analysis.

Results: This study demonstrates that elevated maternal serum 25(OH)D levels are associated with a decreased risk of preterm labour and various pregnancy-related health issues, highlighting the protective benefits of adequate vitamin D during pregnancy.

Conclusion: Vitamin D supplementation during pregnancy at a dose of 2,000 IU or higher is preventive for pre-eclampsia, insulin resistance, and the development of bronchial asthma in early childhood. Vitamin D screening is indicated for all pregnant women. Dosages of vitamin D preparations should be determined individually, considering laboratory tests and risk factors.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.20
自引率
4.80%
发文量
44
审稿时长
6-12 weeks
期刊介绍: This journal covers the most active and promising areas of current research in gynecology and obstetrics. Invited, well-referenced reviews by noted experts keep readers in touch with the general framework and direction of international study. Original papers report selected experimental and clinical investigations in all fields related to gynecology, obstetrics and reproduction. Short communications are published to allow immediate discussion of new data. The international and interdisciplinary character of this periodical provides an avenue to less accessible sources and to worldwide research for investigators and practitioners.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信