一例继发于慢性淋巴细胞白血病并发展为慢性髓细胞白血病的老年男性罕见病例

Q3 Medicine

European journal of case reports in internal medicine Pub Date : 2024-03-01 DOI:10.12890/2024_004297

S. Saowapa, W. Pangkanon, Yaw Adu, Nattanicha Chaisrimaneepan, Diego Olavarria Bernal, N. Polpichai, Pharit Siladech, Jasmine Sekhon

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引用次数: 0

摘要

慢性淋巴细胞白血病（CLL）是一种淋巴细胞增生性疾病，其特点是单克隆 B 淋巴细胞聚集，继发癌症的风险增加。CLL 和慢性髓性白血病（CML）并存是一种罕见的现象，主要分为三种类型：CML先于CLL、CLL先于CML和同时发生。这些慢性白血病的并存给临床带来了复杂的挑战，其关联的内在机制至今仍是个谜。在此，我们报告了一名有长期 CLL 病史的老年男性，他随后被诊断为继发性 CML。

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A rare case of an elderly male with progression to chronic myeloid leukaemia secondary to chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a lymphoproliferative disorder characterised by an accumulation of monoclonal B lymphocytes, with an increased risk of secondary cancers. The coexistence of CLL and chronic myeloid leukaemia (CML) is a rare phenomenon, with three main types being classified: CML preceding CLL, CLL preceding CML and simultaneous occurrence. The coexistence of these chronic leukaemias poses a complex clinical challenge, with the underlying mechanisms of their association remaining enigmatic. Here, we present a report of an elderly male with a long history of CLL, who was subsequently diagnosed with secondary CML.

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来源期刊

European journal of case reports in internal medicine

CiteScore

2.10

自引率

0.00%

发文量

166

审稿时长

8 weeks

期刊介绍： The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.