J. Essindi, Jacky Njiki Bikoï, Carol Sake, D. S. Mbaga, Arnaud Franck Elang, C. Mikangue, Aicha Ngoutane, Alexandra Emmanuelle Membangbi, Sabine Aimée Touangnou-Chamda, S. R. Essama
{"title":"喀麦隆中部地区 15 岁以上人群对乙型肝炎疫苗无反应的评估：横断面研究","authors":"J. Essindi, Jacky Njiki Bikoï, Carol Sake, D. S. Mbaga, Arnaud Franck Elang, C. Mikangue, Aicha Ngoutane, Alexandra Emmanuelle Membangbi, Sabine Aimée Touangnou-Chamda, S. R. Essama","doi":"10.9734/mrji/2024/v34i11424","DOIUrl":null,"url":null,"abstract":"Background: To investigate the risks factors associated to the non-response of hepatitis B (HB) immunization in participants over the age of 15 years. \nMethods: From October 2020 to December 2021, data were collected from individuals aged over 15 years who receive at least one dose of vaccine. An algorithm consisted of three (03) tests researching anti-HBs whose detectability threshold was 10 IU/L and anti-HBc. \nResults: A total of 330 participants were included in this study, among which 158 received three doses of vaccine, of these 83.59% and 6,6% were found positive respectively to anti HBs and anti-HBc. We noted that, age [30 – 40] years [OR= 2.41; CI at 95% (1.24 – 4.80)]; single status [OR=10.80; CI at 95% (1.78 – 114.8)], obesity [OR=2.99; CI at 95% (1.13 – 7.27)], alcohol [OR=10.80; CI at 95% (1.78 – 114.8)]; HEPATITIS vaccine [OR=3.40; CI at 95% (1.24 – 9.10)] were associated with non-response to hepatitis B vaccines. \nConclusion: Non-response to hepatitis B vaccination has been influenced by several risk factors that should be considered during the vaccination process.","PeriodicalId":18450,"journal":{"name":"Microbiology Research Journal International","volume":"19 16","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Non-response to Hepatitis B Vaccines in Individuals Over 15 Years in the Centre Region of Cameroon: A Cross-sectional Study\",\"authors\":\"J. Essindi, Jacky Njiki Bikoï, Carol Sake, D. S. Mbaga, Arnaud Franck Elang, C. Mikangue, Aicha Ngoutane, Alexandra Emmanuelle Membangbi, Sabine Aimée Touangnou-Chamda, S. R. Essama\",\"doi\":\"10.9734/mrji/2024/v34i11424\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: To investigate the risks factors associated to the non-response of hepatitis B (HB) immunization in participants over the age of 15 years. \\nMethods: From October 2020 to December 2021, data were collected from individuals aged over 15 years who receive at least one dose of vaccine. An algorithm consisted of three (03) tests researching anti-HBs whose detectability threshold was 10 IU/L and anti-HBc. \\nResults: A total of 330 participants were included in this study, among which 158 received three doses of vaccine, of these 83.59% and 6,6% were found positive respectively to anti HBs and anti-HBc. We noted that, age [30 – 40] years [OR= 2.41; CI at 95% (1.24 – 4.80)]; single status [OR=10.80; CI at 95% (1.78 – 114.8)], obesity [OR=2.99; CI at 95% (1.13 – 7.27)], alcohol [OR=10.80; CI at 95% (1.78 – 114.8)]; HEPATITIS vaccine [OR=3.40; CI at 95% (1.24 – 9.10)] were associated with non-response to hepatitis B vaccines. \\nConclusion: Non-response to hepatitis B vaccination has been influenced by several risk factors that should be considered during the vaccination process.\",\"PeriodicalId\":18450,\"journal\":{\"name\":\"Microbiology Research Journal International\",\"volume\":\"19 16\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbiology Research Journal International\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9734/mrji/2024/v34i11424\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbiology Research Journal International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/mrji/2024/v34i11424","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of Non-response to Hepatitis B Vaccines in Individuals Over 15 Years in the Centre Region of Cameroon: A Cross-sectional Study
Background: To investigate the risks factors associated to the non-response of hepatitis B (HB) immunization in participants over the age of 15 years.
Methods: From October 2020 to December 2021, data were collected from individuals aged over 15 years who receive at least one dose of vaccine. An algorithm consisted of three (03) tests researching anti-HBs whose detectability threshold was 10 IU/L and anti-HBc.
Results: A total of 330 participants were included in this study, among which 158 received three doses of vaccine, of these 83.59% and 6,6% were found positive respectively to anti HBs and anti-HBc. We noted that, age [30 – 40] years [OR= 2.41; CI at 95% (1.24 – 4.80)]; single status [OR=10.80; CI at 95% (1.78 – 114.8)], obesity [OR=2.99; CI at 95% (1.13 – 7.27)], alcohol [OR=10.80; CI at 95% (1.78 – 114.8)]; HEPATITIS vaccine [OR=3.40; CI at 95% (1.24 – 9.10)] were associated with non-response to hepatitis B vaccines.
Conclusion: Non-response to hepatitis B vaccination has been influenced by several risk factors that should be considered during the vaccination process.
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