获取用于骨修复和再生的纳米复合水凝胶的先进构建策略

IF 8.6 2区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY
Wang Ding, Yuxiang Ge, Tikai Zhang, Cheng Zhang, Xiaofan Yin
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引用次数: 0

摘要

骨组织工程通过促进持久的血管生成和骨生成,在促进骨重建方面发挥着关键作用。最初采用的是热凝胶复合水凝胶支架技术。然而,为了解决各种局限性,后来又开发了许多凝胶结构,包括成骨结冷胶、半穿透网络水凝胶、光诱导交联甲基丙烯酸酯凝胶和超分子水凝胶。本综述探讨了这些凝胶结构的机理、形成原理和医疗功效。此外,调节人体骨骼生长的新型生物工程技术有望在未来出现。这项工作有望大大加快水凝胶膜在骨修复领域的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Advanced construction strategies to obtain nanocomposite hydrogels for bone repair and regeneration

Advanced construction strategies to obtain nanocomposite hydrogels for bone repair and regeneration

Bone tissue engineering is pivotal in facilitating bone reconstruction by promoting persistent angiogenesis and osteogenesis. Initially, the hot gel composite hydrogel scaffold technique was employed. However, to address various limitations, numerous gel structures have since been developed, including osteogenic gellan gels, semi-interpenetrating network hydrogels, photoinduced crosslinking methacrylate gels, and supramolecular hydrogels. This review examines the mechanisms, formation principles, and medical benefits of these gel structures. In addition, novel bioengineering techniques to regulate human bone growth are expected to emerge in the future. This work is expected to significantly expedite the advancement of hydrogel membranes in the field of bone repair.

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来源期刊
Npg Asia Materials
Npg Asia Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-
CiteScore
15.40
自引率
1.00%
发文量
87
审稿时长
2 months
期刊介绍: NPG Asia Materials is an open access, international journal that publishes peer-reviewed review and primary research articles in the field of materials sciences. The journal has a global outlook and reach, with a base in the Asia-Pacific region to reflect the significant and growing output of materials research from this area. The target audience for NPG Asia Materials is scientists and researchers involved in materials research, covering a wide range of disciplines including physical and chemical sciences, biotechnology, and nanotechnology. The journal particularly welcomes high-quality articles from rapidly advancing areas that bridge the gap between materials science and engineering, as well as the classical disciplines of physics, chemistry, and biology. NPG Asia Materials is abstracted/indexed in Journal Citation Reports/Science Edition Web of Knowledge, Google Scholar, Chemical Abstract Services, Scopus, Ulrichsweb (ProQuest), and Scirus.
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