基于多金属层孔阵列的生物传感器

IF 1.8 4区物理与天体物理 Q2 PHYSICS, MULTIDISCIPLINARY

EPL Pub Date : 2023-12-02 DOI:10.1209/0295-5075/ad11b5

Jindan Duan, Gang Song, Gaoyan Duan, Peilin Lang

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引用次数: 0

摘要

摘要我们提出了一种对被测液体折射率（RI）敏感的生物传感器。该传感器由基于周期性纳米孔阵列的金属-绝缘体-金属结构组成，其吸收光谱在谐振波长处呈现窄峰。有限差分时域法用于模拟所提出的结构。结果表明，在 800 纳米波长处有一个窄的共振峰，RI 为 1.33。通过在下金属层上添加凹槽，最大吸收率增至 99.7%。当 RI 在 1.33 至 1.35 范围内变化时，其灵敏度可达 550 nm /RIU，窄半峰全宽为 5.87 nm，优点系数为 93.7。此外，吸收峰值的变化也很明显，灵敏度为 1845%/RIU，可用于测量牛血清白蛋白和其他溶液的浓度，实现生物传感器。

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Biosensor based on multiple metal layer-hole array

Abstract We propose a biosensor which is sensitive to the refraction index (RI) of the tested liquid. The sensor is composed of a metal-insulator-metal structure based on periodic nanopore arrays, whose absorption spectrum exhibits a narrow peak at the resonant wavelength. The finite difference time domain method is used to simulate the proposed structure. The results show that there is a narrow resonant peak at the wavelength of 800 nm with RI of 1.33. By adding grooves on the lower metal layer, the maximum absorption rate increases to 99.7%. When RI varies in the range from 1.33 to 1.35, it can have a high sensitivity of 550 nm /RIU, a narrow half peak full width of 5.87 nm, and a figure of merit of 93.7. In addition, the absorption peak value also changes significantly with a sensitivity of 1845%/RIU, which can be used to measure the concentration of bovine serum albumin and other solutions to achieve biosensors.

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来源期刊

EPL 物理-物理：综合

CiteScore

3.30

自引率

5.60%

发文量

332

审稿时长

1.9 months

期刊介绍： General physics – physics of elementary particles and fields – nuclear physics – atomic, molecular and optical physics – classical areas of phenomenology – physics of gases, plasmas and electrical discharges – condensed matter – cross-disciplinary physics and related areas of science and technology. Letters submitted to EPL should contain new results, ideas, concepts, experimental methods, theoretical treatments, including those with application potential and be of broad interest and importance to one or several sections of the physics community. The presentation should satisfy the specialist, yet remain understandable to the researchers in other fields through a suitable, clearly written introduction and conclusion (if appropriate). EPL also publishes Comments on Letters previously published in the Journal.