螺钉固定术后人体脊椎损伤的相场建模与模拟

IF 3.7 2区 工程技术 Q1 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS
Deison Preve, Pietro Lenarda, Daniele Bianchi, Alessio Gizzi
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引用次数: 0

摘要

本研究利用相场模型对人类脊椎在压缩条件下切开椎弓根螺钉后的断裂模式、变形机制、损伤和机械响应进行了数值模拟和研究。此外,考虑到椎体的几种模拟生理运动,所提出的相场框架可以阐明脊柱融合手术后不同损伤模式(如裂纹成核点和裂纹轨迹)发挥作用的情况。空间异质弹性特性和相场参数是通过骨密度估算计算得出的。对椎体-螺钉模型进行了收敛性分析,考虑了几种网格细化方法,结果表明与现有的相关文献有很好的一致性。因此,通过假设椎弓根螺钉插入的不同角度,并考虑到几种椎体运动加载机制,得出了大量描述椎体模型内损伤特征的数值结果。总之,相场结果证实并丰富了现有文献,为医学界提供了启示,这将有助于加强临床干预,减少术后骨质破坏和螺钉松动。所提出的计算方法还研究了不同转移性病变中椎体-螺钉体的断裂和机械行为对重大生命威胁的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Phase field modelling and simulation of damage occurring in human vertebra after screws fixation procedure

Phase field modelling and simulation of damage occurring in human vertebra after screws fixation procedure

The present endeavour numerically exploits the use of a phase-field model to simulate and investigate fracture patterns, deformation mechanisms, damage, and mechanical responses in a human vertebra after the incision of pedicle screws under compressive regimes. Moreover, the proposed phase field framework can elucidate scenarios where different damage patterns, such as crack nucleation sites and crack trajectories, play a role after the spine fusion procedure, considering several simulated physiological movements of the vertebral body. Spatially heterogeneous elastic properties and phase field parameters have been computationally derived from bone density estimation. A convergence analysis has been conducted for the vertebra-screws model, considering several mesh refinements, which has demonstrated good agreement with the existing literature on this topic. Consequently, by assuming different angles for the insertion of the pedicle screws and taking into account a few vertebral motion loading regimes, a plethora of numerical results characterizing the damage occurring within the vertebral model has been derived. Overall, the phase field results confirm and enrich the current literature, shed light on the medical community, which will be useful in enhancing clinical interventions and reducing post-surgery bone failure and screw loosening. The proposed computational approach also investigates the effects in terms of fracture and mechanical behaviour of the vertebral-screws body within different metastatic lesions opening towards major life threatening scenarios.

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来源期刊
Computational Mechanics
Computational Mechanics 物理-力学
CiteScore
7.80
自引率
12.20%
发文量
122
审稿时长
3.4 months
期刊介绍: The journal reports original research of scholarly value in computational engineering and sciences. It focuses on areas that involve and enrich the application of mechanics, mathematics and numerical methods. It covers new methods and computationally-challenging technologies. Areas covered include method development in solid, fluid mechanics and materials simulations with application to biomechanics and mechanics in medicine, multiphysics, fracture mechanics, multiscale mechanics, particle and meshfree methods. Additionally, manuscripts including simulation and method development of synthesis of material systems are encouraged. Manuscripts reporting results obtained with established methods, unless they involve challenging computations, and manuscripts that report computations using commercial software packages are not encouraged.
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