RyR2磷酸化改变了二联体结构。

IF 3.3 2区医学 Q1 PHYSIOLOGY

Journal of General Physiology Pub Date : 2024-04-01 Epub Date: 2024-03-07 DOI:10.1085/jgp.202413569

Ben Short

引用次数: 0

摘要

JGP 研究（Asghari 等人，2024 年。J. Gen. Physiol.https://doi.org/10.1085/jgp.202213108）表明，β-肾上腺素能信号传导会扩大二联体并重组心肌细胞中的 RyR2 四聚体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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RyR2 phosphorylation alters dyad architecture.

JGP study (Asghari et al. 2024. J. Gen. Physiol.https://doi.org/10.1085/jgp.202213108) indicates that β-adrenergic signaling enlarges dyads and reorganizes RyR2 tetramers in cardiomyocytes.

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来源期刊

Journal of General Physiology 医学-生理学

CiteScore

6.00

自引率

10.50%

发文量

审稿时长

6-12 weeks

期刊介绍： General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization. The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.