腹腔镜胆囊切除术后恶心和呕吐发生率与预处理氟哌啶醇和昂丹司琼的比较:随机临床试验研究。

IF 1.1 4区 医学 Q3 SURGERY
Ali Karami, Elisa Ramadani, Mahsa Banifatemi, Naeimehossadat Asmarian, Zeinabsadat Fattahi Saravi
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引用次数: 0

摘要

目的:手术后恶心和呕吐是最常见的并发症。因此,我们进行了这项研究,比较昂丹司琼和氟哌啶醇对腹腔镜胆囊切除术后恶心和呕吐的影响:在这项随机临床试验中,60名择期接受腹腔镜胆囊切除术的患者被分配到氟哌啶醇组(0.05 mg/kg,n = 30)和昂丹司琼组(0.15 mg/kg,n = 30)。采用眼部模拟量表评估术后恶心和呕吐。术后 6 小时内,每隔 15 分钟在恢复室测量一次心率和血压。此外,还对患者的术后满意度进行了评估:结果:氟哌啶醇和昂丹司琼对恢复室和病房的术后恶心和呕吐具有相同的效果。研究发现,氟哌啶醇组和昂丹司琼组在恢复室的视觉模拟量表变量变化趋势相似(P = 0.58);在病房也是如此(P = 0.79)。两组患者在恢复室的停留时间比较无统计学意义(P = 0.19)。此外,两组患者的术后满意度也没有差异(P = 0.82):结论:氟哌啶醇和昂丹司琼在减少腹腔镜胆囊切除术后恢复室和病房的恶心和呕吐方面效果相当。两组患者的满意度和在恢复室停留的时间没有差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Nausea and Vomiting Incidence After Laparoscopic Cholecystectomy With Pretreatment With Haloperidol and Ondansetron: A Randomization Clinical Trial Study.

Objective: Nausea and vomiting after surgery are the most common complications. Therefore, we performed this study to compare the effect of ondansetron and haloperidol on nausea and vomiting after laparoscopic cholecystectomy.

Patients and methods: In this randomized clinical trial, 60 patients candidates for elective laparoscopic cholecystectomy were allocated to haloperidol (0.05 mg/kg, n = 30) and ondansetron (0.15 mg/kg, n = 30) groups. An Ocular Analog Scale was used to assess postoperative nausea and vomiting. Every 15 minutes in the recovery room, heart rate and blood pressure were measured up to 6 hours after surgery. In addition, patient satisfaction was assessed postoperatively.

Results: Haloperidol and ondansetron have the same effect on postoperative nausea and vomiting in the recovery room and ward. It was found that the trend of Visual Analog Scale variable changes in the recovery room was similar in the haloperidol and ondansetron group ( P = 0.58); it was also true for the ward ( P = 0.79). Comparing the length of stay in a recovery room in the 2 groups was not statistically significant ( P = 0.19). In addition, the 2 groups did not differ in satisfaction postoperatively ( P = 0.82).

Conclusion: Haloperidol and ondansetron had an equal effect on reducing nausea and vomiting in the recovery room and ward after laparoscopic cholecystectomy. Patient satisfaction and length of stay in the recovery room did not differ between groups.

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来源期刊
CiteScore
2.00
自引率
10.00%
发文量
103
审稿时长
3-8 weeks
期刊介绍: Surgical Laparoscopy Endoscopy & Percutaneous Techniques is a primary source for peer-reviewed, original articles on the newest techniques and applications in operative laparoscopy and endoscopy. Its Editorial Board includes many of the surgeons who pioneered the use of these revolutionary techniques. The journal provides complete, timely, accurate, practical coverage of laparoscopic and endoscopic techniques and procedures; current clinical and basic science research; preoperative and postoperative patient management; complications in laparoscopic and endoscopic surgery; and new developments in instrumentation and technology.
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