心脏并发症与 COVID-19:威胁生命的并发症回顾。

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Zeinab Eftekhar, Habib Haybar, Alireza Mohebbi, Najmaldin Saki
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引用次数: 0

摘要

2019年新型冠状病毒病(COVID-19)于2019年12月最后几天在中国武汉首次报告。包括心血管疾病(CVDs)在内的某些并发症的存在是导致COVID-19患者预后更差的基础。以 COVID-19、SARS-CoV-2、心力衰竭、心肌梗死、心律失常和心脏并发症为关键词,在谷歌学术搜索引擎和 PubMed 数据库中搜索并检索了截至 2023 年的相关英文文献。血流动力学负荷增加、缺血相关功能障碍、心室重塑、过度神经体液刺激、心肌细胞钙循环异常以及细胞外基质增殖过度或不足与 COVID-19 患者的心力衰竭(HF)有关。炎症细胞因子的过度释放导致的炎症反应会导致这些患者发生心肌梗死(MI)。病毒可通过心脏并发症、缺氧、心脏血流动力学下降和显著的炎症标志物诱发心律失常。此外,研究还发现 COVID-19 的心脏并发症与不良预后、住院时间延长和死亡率增加有关。COVID-19 和心血管疾病患者的死亡风险较高,在住院期间接受治疗和重症监护时应给予高度重视。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiac Complications and COVID-19: A Review of Life-threatening Co-morbidities.

The novel 2019 coronavirus disease (COVID-19) was first reported in the last days of December 2019 in Wuhan, China. The presence of certain co-morbidities, including cardiovascular diseases (CVDs), are the basis for worse outcomes in patients with COVID-19. Relevant English-language literature was searched and retrieved from the Google Scholar search engine and PubMed database up to 2023 using COVID-19, SARS-CoV-2, Heart failure, Myocardial infarction, and Arrhythmia and Cardiac complication as keywords. Increased hemodynamic load, ischemia-related dysfunction, ventricular remodeling, excessive neurohumoral stimulation, abnormal myocyte calcium cycling, and excessive or insufficient extracellular matrix proliferation are associated with heart failure (HF) in COVID-19 patients. Inflammatory reaction due to the excessive release of inflammatory cytokines, leads to myocardial infarction (MI) in these patients. The virus can induce heart arrhythmia through cardiac complications, hypoxia, decreased heart hemodynamics, and remarkable inflammatory markers. Moreover, studies have linked cardiac complications in COVID-19 with poor outcomes, extended hospitalization time, and increased mortality rate. Patients with COVID-19 and CVDs are at higher mortality risk and they should be given high priority when receiving the treatment and intensive care during hospitalization.

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来源期刊
Current Cardiology Reviews
Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.70
自引率
10.50%
发文量
117
期刊介绍: Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.
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