{"title":"埃塞俄比亚东南部临床主诉消化不良和过敏性疾病的政府雇员中幽门螺杆菌感染的负担和风险因素：一项多机构横断面研究。","authors":"Taye Kebede, Hagos Ashenafi","doi":"10.2147/RRTM.S447203","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong><i>Helicobacter pylori</i> (<i>H. pylori</i>) is believed to have spread from East Africa, but its burden is still unknown in less privileged regions of Ethiopia. Indigestion is an upset stomach, upper abdomen discomfort, heartburn, and bloating. This study evaluated the burden and risk factors for <i>H. pylori</i> infection among government employees who clinically complained of indigestion but allergic diseases in five public health institutions in Southeastern Ethiopia.</p><p><strong>Methods: </strong>A health facilities-based cross-sectional survey study was conducted in Southeastern Ethiopia from March to November 2022, employing cluster sampling. Blood specimens, clinical data, and semi-structured questionnaires about risk factors were collected. Data analysis was conducted using descriptive, bivariate, and multivariable logistic regression in STATA software, Windows version 16.1.</p><p><strong>Results: </strong>The overall prevalence of infection was found to be 77.6%. The sampled health institution (<i>ρ</i>-value < 0.05), engagement in sideline business (<i>ρ</i>-value < 0.05), sharing local spoon on meal [AOR = 39.30; CI:19.52 -78.31; <i>ρ</i>-value < 0.001], admitting \"Gursha\" during meal [AOR = 71.48; CI:3.99 -1279.77; <i>ρ</i>-value < 0.05], the toilet type [AOR = 1410.98; CI:121.16 -16,431.19; <i>ρ</i>-value < 0.001], alcohol drinking [AOR = 15.15; CI:1.90 -120.62; <i>ρ</i>-value < 0.05], sleeping hours length [AOR = 15.01; CI:13.48-55.96; <i>ρ</i>-value < 0.001], chewing Khat [AOR = 76.73; CI:8.57-687.07; <i>ρ</i>-value < 0.001], and regular hand washing before eating [AOR = 0.15; CI:0.12-0.19; <i>ρ</i>-value < 0.05] were the independent predictors of <i>H. pylori</i> infection.</p><p><strong>Conclusion: </strong>The prevalence rate of <i>H. pylori</i> infection in Southeastern Ethiopia is agonizingly high, exceeding the world average by 27.6%, the first report, and seems to be one of the neglected infectious diseases. Hence, the Oromia Region Health Bureau should reinvigorate the basic infectious disease control methods, establish routine laboratory diagnostic platforms, and intervene in selected societal practices spreading infections.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"15 ","pages":"25-49"},"PeriodicalIF":3.1000,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10885702/pdf/","citationCount":"0","resultStr":"{\"title\":\"The Burden and Risk Factors of <i>Helicobacter Pylori</i> Infection Among Government Employees Who Clinically Complain of Indigestion but Allergic Diseases in Southeastern Ethiopia: A Multi-Institution Cross-Sectional Study.\",\"authors\":\"Taye Kebede, Hagos Ashenafi\",\"doi\":\"10.2147/RRTM.S447203\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong><i>Helicobacter pylori</i> (<i>H. pylori</i>) is believed to have spread from East Africa, but its burden is still unknown in less privileged regions of Ethiopia. Indigestion is an upset stomach, upper abdomen discomfort, heartburn, and bloating. This study evaluated the burden and risk factors for <i>H. pylori</i> infection among government employees who clinically complained of indigestion but allergic diseases in five public health institutions in Southeastern Ethiopia.</p><p><strong>Methods: </strong>A health facilities-based cross-sectional survey study was conducted in Southeastern Ethiopia from March to November 2022, employing cluster sampling. Blood specimens, clinical data, and semi-structured questionnaires about risk factors were collected. Data analysis was conducted using descriptive, bivariate, and multivariable logistic regression in STATA software, Windows version 16.1.</p><p><strong>Results: </strong>The overall prevalence of infection was found to be 77.6%. The sampled health institution (<i>ρ</i>-value < 0.05), engagement in sideline business (<i>ρ</i>-value < 0.05), sharing local spoon on meal [AOR = 39.30; CI:19.52 -78.31; <i>ρ</i>-value < 0.001], admitting \\\"Gursha\\\" during meal [AOR = 71.48; CI:3.99 -1279.77; <i>ρ</i>-value < 0.05], the toilet type [AOR = 1410.98; CI:121.16 -16,431.19; <i>ρ</i>-value < 0.001], alcohol drinking [AOR = 15.15; CI:1.90 -120.62; <i>ρ</i>-value < 0.05], sleeping hours length [AOR = 15.01; CI:13.48-55.96; <i>ρ</i>-value < 0.001], chewing Khat [AOR = 76.73; CI:8.57-687.07; <i>ρ</i>-value < 0.001], and regular hand washing before eating [AOR = 0.15; CI:0.12-0.19; <i>ρ</i>-value < 0.05] were the independent predictors of <i>H. pylori</i> infection.</p><p><strong>Conclusion: </strong>The prevalence rate of <i>H. pylori</i> infection in Southeastern Ethiopia is agonizingly high, exceeding the world average by 27.6%, the first report, and seems to be one of the neglected infectious diseases. Hence, the Oromia Region Health Bureau should reinvigorate the basic infectious disease control methods, establish routine laboratory diagnostic platforms, and intervene in selected societal practices spreading infections.</p>\",\"PeriodicalId\":21138,\"journal\":{\"name\":\"Research and Reports in Tropical Medicine\",\"volume\":\"15 \",\"pages\":\"25-49\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2024-02-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10885702/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research and Reports in Tropical Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/RRTM.S447203\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research and Reports in Tropical Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/RRTM.S447203","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
The Burden and Risk Factors of Helicobacter Pylori Infection Among Government Employees Who Clinically Complain of Indigestion but Allergic Diseases in Southeastern Ethiopia: A Multi-Institution Cross-Sectional Study.
Background: Helicobacter pylori (H. pylori) is believed to have spread from East Africa, but its burden is still unknown in less privileged regions of Ethiopia. Indigestion is an upset stomach, upper abdomen discomfort, heartburn, and bloating. This study evaluated the burden and risk factors for H. pylori infection among government employees who clinically complained of indigestion but allergic diseases in five public health institutions in Southeastern Ethiopia.
Methods: A health facilities-based cross-sectional survey study was conducted in Southeastern Ethiopia from March to November 2022, employing cluster sampling. Blood specimens, clinical data, and semi-structured questionnaires about risk factors were collected. Data analysis was conducted using descriptive, bivariate, and multivariable logistic regression in STATA software, Windows version 16.1.
Results: The overall prevalence of infection was found to be 77.6%. The sampled health institution (ρ-value < 0.05), engagement in sideline business (ρ-value < 0.05), sharing local spoon on meal [AOR = 39.30; CI:19.52 -78.31; ρ-value < 0.001], admitting "Gursha" during meal [AOR = 71.48; CI:3.99 -1279.77; ρ-value < 0.05], the toilet type [AOR = 1410.98; CI:121.16 -16,431.19; ρ-value < 0.001], alcohol drinking [AOR = 15.15; CI:1.90 -120.62; ρ-value < 0.05], sleeping hours length [AOR = 15.01; CI:13.48-55.96; ρ-value < 0.001], chewing Khat [AOR = 76.73; CI:8.57-687.07; ρ-value < 0.001], and regular hand washing before eating [AOR = 0.15; CI:0.12-0.19; ρ-value < 0.05] were the independent predictors of H. pylori infection.
Conclusion: The prevalence rate of H. pylori infection in Southeastern Ethiopia is agonizingly high, exceeding the world average by 27.6%, the first report, and seems to be one of the neglected infectious diseases. Hence, the Oromia Region Health Bureau should reinvigorate the basic infectious disease control methods, establish routine laboratory diagnostic platforms, and intervene in selected societal practices spreading infections.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
