T1 直肠癌非根治性内窥镜切除术后的处理方法

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Hao Dang, Daan A. Verhoeven, Jurjen J. Boonstra, Monique E. van Leerdam
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引用次数: 0

摘要

自开展人群筛查以来,越来越多的 T1 直肠癌被发现并通过局部内镜切除术切除。仅靠内镜切除术就能治愈患者,但初次切除后仍有可能残留肿瘤细胞。这些残留细胞可能位于切除部位的腔内,也可能以(淋巴结)转移的形式存在于腔外。为了降低残留细胞向更晚期疾病发展的风险,通常需要进行额外的治疗。然而,就目前可用的风险分层模型而言,确定非根治性内镜切除术后哪些患者应该或不应该接受进一步治疗仍具有挑战性。在这篇综述中,我们讨论了未经根治性治疗的 T1 直肠癌患者的不同治疗策略,以及每种策略的现有证据和临床决策的相关注意事项。此外,我们还为 T1 直肠癌非根治性内镜切除术后的管理和监测提供了实用指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management after non-curative endoscopic resection of T1 rectal cancer

Since the introduction of population-based screening, increasing numbers of T1 rectal cancers are detected and removed by local endoscopic resection. Patients can be cured with endoscopic resection alone, but there is a possibility of residual tumor cells remaining after the initial resection. These can be located intraluminally at the resection site or extraluminally in the form of (lymph node) metastases. To decrease the risk of residual cells progressing towards more advanced disease, additional treatment is usually needed. However, with the currently available risk stratification models, it remains challenging to determine who should and should not be further treated after non-curative endoscopic resection. In this review, the different management strategies for patients with non-curatively treated T1 rectal cancers are discussed, along with the available evidence for each strategy and relevant considerations for clinical decision making. Furthermore, we provide practical guidance on the management and surveillance following non-curative endoscopic resection of T1 rectal cancer.

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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
23
审稿时长
69 days
期刊介绍: Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.
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