[股骨骨膜旁骨肉瘤和闰假体救治手术。三级医院的经验和手术技巧]。

Acta ortopedica mexicana Pub Date : 2023-09-01
M Vilchis-Ramírez, F A Álvarez-Martínez, M E Tena-Sanabria, G Fuentes-Herrera
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引用次数: 0

摘要

导言:骨膜旁骨肉瘤是一种髓外恶性骨肿瘤,细胞会产生类骨质,占所有骨肉瘤的 5%以下,主要发生在第二至第四个十年的女性身上。它通常位于股骨远端和胫骨近端。临床表现为体积增大、大腿或膝盖疼痛。由于股骨骨旁骨肉瘤发病率低且临床特征不明显,本文介绍了一例股骨骨旁骨肉瘤的临床病例,并介绍了手术技巧。放射学检查显示她的骨病变具有恶性特征,因此她被送往三级甲等医院,在那里制定了肿瘤学研究方案;包括用 Jamshidi 针对病变进行两次经皮活检,组织病理学报告显示恶性细胞为阴性。肺部高分辨率计算机断层扫描显示有转移灶,Tc-99m MDP 骨闪烁扫描显示右股骨轴的成骨细胞活性增加。结论:在股骨骨膜旁骨肉瘤患者的肢体修复手术中,椎间假体是一种合适的治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Parosteal osteosarcoma of the femur and salvage surgery with intercalary prosthesis. Experience in a third level unit and surgical technique].

Introduction: parosteal osteosarcoma is an extramedullary malignant bone tumor in which cells produce osteoid, represents less than 5% of all osteosarcomas, it occurs predominantly in women between the second and fourth decade of life. It is often located in the distal region of the femur and proximal tibia. Clinically it presents with increased volume and thigh or knee pain. Due to its low incidence and clinical features, a clinical case of femoral parosteal osteosarcoma is presented, with description of the surgical technique performed.

Case report: a 14-year-old female presented with a 6-month history of increased volume and right thigh pain. Radiological studies revealed a bone lesion with malignant characteristics, for which she was sent to third-level hospital where oncology study protocol was set up; consisting in two percutaneous biopsies of the lesion with Jamshidi needle, which were histopathology reported as negative for malignant cells. The pulmonary high-resolution computed tomography showed metastasis and a Tc-99m MDP bone scintigraphy showed increased osteoblastic activity in the right femoral shaft. Given the results, is confirmed the need of en-bloc resection and intercalary prosthesis implantation with adjuvant chemotherapy.

Conclusion: the intercalary prosthesis is a suitable therapeutic option in limb-salvage surgery for patients with femoral parosteal osteosarcoma.

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