流动溶液中的拉曼和表面增强拉曼散射检测用于复杂混合物分析

IF 5.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Annual Review of Analytical Chemistry Pub Date : 2024-02-21 DOI:10.1146/annurev-anchem-061522-035207

Monika Poonia, Courtney J. Morder, Hannah C. Schorr, Zachary D. Schultz

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引用次数: 0

摘要

拉曼散射为识别和量化流动溶液中的分子提供了一种化学特异性的无标记方法。本综述全面探讨了拉曼光谱和表面增强拉曼散射（SERS）在流动液体样品中的应用。我们总结了利用拉曼和 SERS 分析进行在线和在线检测的发展情况，包括微流体设备的设计、独特 SERS 基底的开发、新型采样界面，以及将这些方法与基于流体的化学分离（如色谱法和电泳法）相结合。文章强调了与这些技术相关的挑战和局限性，并举例说明了这些技术在化学、生物和环境科学等多个领域的应用。总之，这篇综述展示了拉曼和 SERS 在分析复杂混合物方面的实用性，并强调了进一步开发和优化这些技术的潜力。《分析化学年度综述》第 17 卷的最终在线出版日期预计为 2024 年 5 月。修订后的预计日期请参见 http://www.annualreviews.org/page/journal/pubdates。

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Raman and Surface-Enhanced Raman Scattering Detection in Flowing Solutions for Complex Mixture Analysis

Raman scattering provides a chemical-specific and label-free method for identifying and quantifying molecules in flowing solutions. This review provides a comprehensive examination of the application of Raman spectroscopy and surface-enhanced Raman scattering (SERS) to flowing liquid samples. We summarize developments in online and at-line detection using Raman and SERS analysis, including the design of microfluidic devices, the development of unique SERS substrates, novel sampling interfaces, and coupling these approaches to fluid-based chemical separations (e.g., chromatography and electrophoresis). The article highlights the challenges and limitations associated with these techniques and provides examples of their applications in a variety of fields, including chemistry, biology, and environmental science. Overall, this review demonstrates the utility of Raman and SERS for analysis of complex mixtures and highlights the potential for further development and optimization of these techniques.Expected final online publication date for the Annual Review of Analytical Chemistry, Volume 17 is May 2024. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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来源期刊

Annual Review of Analytical Chemistry CHEMISTRY, ANALYTICAL-SPECTROSCOPY

CiteScore

14.80

自引率

1.20%

发文量

期刊介绍： The Annual Review of Analytical Chemistry, launched in 2008, offers a comprehensive perspective on the field, drawing from diverse disciplines such as biology, physics, and engineering, with analytical chemistry as the central theme. The journal's current volume has transitioned from gated to open access through Annual Reviews' Subscribe to Open program, with all articles published under a CC BY license.