内窥镜经蝶垂体腺瘤切除术后使用生物可吸收板进行ellar重建：安全有效

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

Annals of Otology Rhinology and Laryngology Pub Date : 2024-05-01 Epub Date: 2024-02-19 DOI:10.1177/00034894241233870

Ryan Kendall Thorpe, Mark C Dougherty, Jarrett E Walsh, Scott M Graham, Jeremy D W Greenlee

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引用次数: 0

摘要

目的报告一大批接受内窥镜经鼻蝶手术（EETS）切除垂体腺瘤并随后进行Resorb-X板（RXP）蝶窦重建的患者的治疗结果：方法：对2005年至2020年间在一家学术中心进行的620例EETS手术进行回顾性研究：结果：2012年至2020年间，共有208名患者接受了215例EETS手术，这些患者在垂体肿瘤切除术后接受了RXP重建，最终病理诊断为垂体腺瘤。汇总数据分析显示，术前平均肿瘤体积为 6.8 立方厘米（范围：0.038-51.03 立方厘米）。2例患者（0.93%）术后出现脑脊液漏。1例患者（0.47%）发生术后脑膜炎。没有 RXP 挤压的病例：使用 RXP 重建蝶鞍后，术后 CSF 渗漏和脑膜炎的发生率优于其他方法，包括使用自体移植物和皮瓣。在 EETS 期间使用 RXP 是一种安全有效的蝶窦重建方法，可避免垂体腺瘤切除术后自体组织重建的需要。

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Sellar Reconstruction With a Bioabsorbable Plate After Endoscopic Transsphenoidal Pituitary Adenoma Resection: Safe and Efficacious.

Objective: To report outcomes of a large cohort of patients who underwent endoscopic endonasal transsphenoidal surgery (EETS) for resection of a pituitary adenoma with subsequent Resorb-X plate (RXP) sellar reconstruction.

Methods: A retrospective review of 620 EETS operations performed at a single academic center between 2005 and 2020 was conducted.

Results: A total of 215 EETS operations of 208 patients were identified between 2012 and 2020 who underwent reconstruction with the RXP after EETS for pituitary tumor resection with a final pathologic diagnosis of pituitary adenoma. Analysis of pooled data revealed a mean preoperative tumor volume of 6.8 cm³ (range: 0.038-51.03 cm³). Postoperative cerebrospinal fluid leak occurred in 2 patients (0.93%). Postoperative meningitis occurred in 1 patient (0.47%). There were no cases of RXP extrusion.

Conclusions: The rate of postoperative CSF leak and meningitis after use of the RXP for sellar reconstruction compares favorably to other methods, including use of autologous grafts and flaps. Use of RXP during EETS is a safe and efficacious method of sellar reconstruction and may obviate the need for autologous tissue reconstruction after pituitary adenoma resection.

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来源期刊

Annals of Otology Rhinology and Laryngology 医学-耳鼻喉科学

CiteScore

3.10

自引率

7.10%

发文量

171

审稿时长

4-8 weeks

期刊介绍： The Annals of Otology, Rhinology & Laryngology publishes original manuscripts of clinical and research importance in otolaryngology–head and neck medicine and surgery, otology, neurotology, bronchoesophagology, laryngology, rhinology, head and neck oncology and surgery, plastic and reconstructive surgery, pediatric otolaryngology, audiology, and speech pathology. In-depth studies (supplements), papers of historical interest, and reviews of computer software and applications in otolaryngology are also published, as well as imaging, pathology, and clinicopathology studies, book reviews, and letters to the editor. AOR is the official journal of the American Broncho-Esophagological Association.