制药业中的生物聚合物包装材料

Kosana Popović, Slađana Živanović, Ivana Jevtić
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引用次数: 0

摘要

出于对环境的考虑,生物聚合物包装材料在制药行业的地位日益突出。这些生物聚合物来源于可再生资源,具有生物降解性、生物相容性和无毒性,是各种制药应用的理想选择。在给药方面,生物聚合物在控释配方中发挥着至关重要的作用,尤其是在个性化药物和生物制药产品方面。水凝胶是一种三维聚合物网络,是模拟活组织、促进刺激响应型药物释放并将毒副作用降至最低的关键。制剂策略包括扩散控制、降解控制或环境触发释放。生物降解系统使用聚(乳酸)和聚(乙醇酸)等聚合物,通过控制降解来实现可持续给药。渗透给药系统利用渗透压控制药物释放,而刺激响应式设计则对环境变化做出反应。将生物聚合物融入药品包装符合生态友好型实践,解决了传统石油基材料带来的挑战。这种转变标志着一种与环境保护相协调的可持续和创新的药品包装方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biopolymer Packaging Materials in the Pharmaceutical Industry
Biopolymer packaging materials are gaining prominence in the pharmaceutical industry due to environmental concerns. Derived from renewable sources, these biopolymers offer biodegradability, biocompatibility, and non-toxicity, making them ideal for various pharmaceutical applications. In drug delivery, biopolymers play a crucial role in controlled release formulations, especially for personalized medicines and biopharmaceutical products. Hydrogels, three-dimensional polymer networks, are key in mimicking living tissues and facilitating stimuli-responsive drug release with minimal toxic effects. The formulation strategies involve diffusion-controlled, degradation-controlled, or environmentally triggered release. Biodegradable systems, using polymers like poly(lactic acid) and poly(glycolic acid), contribute to sustainable drug delivery by undergoing controlled degradation. Osmotic delivery systems leverage osmotic pressure for controlled drug release, while stimuli-responsive designs respond to environmental changes. Biopolymer integration in pharmaceutical packaging aligns with eco-friendly practices, addressing challenges posed by traditional petroleum-based materials. This shift signifies a sustainable and innovative approach to pharmaceutical packaging in harmony with environmental preservation.
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