Comparison of effectiveness of combination of xylocaine and dexmedetomidine with xylocaine alone in biers block of upper limb.

Objective: To evaluate two groups (combination versus xylocaine alone) in terms of onset of motor block, duration of block, and postoperative analgesia following the release of the tourniquet. Study Design: Quasi Experimental study. Setting: Chaudhary Muhammad Akram Teaching & Research Hospital. Period: 01 June 2023 to 30 Nov 2023. Material & Methods: Quasi experimental study design with a sample of total 80 patients divided into two groups of 40 each (xylocaine alone & combination of xylocaine and dexmedetomidine) were selected by using non probability convenient sampling technique. Results: Combining dexmedetomidine with xylocaine in Bier's block for upper limb surgery demonstrated significant advantages. Group B exhibited faster onset (3.8 min), prolong motor block, and prolonged postoperative analgesia (12.4 hrs) compared to group A (xylocaine alone: 5.2 min onset & shorter postoperative analgesia 6.8 hrs). Dexmedetomidine enhanced post-operative pain control, showcasing its effectiveness in improving outcomes for Bier's block procedures. Conclusion: Dexmedetomidine enhances Bier's block with xylocaine, providing faster onset, extended motor block, and superior post-operative analgesia for upper limb surgery.