用于生物研究的模块化机器人平台:细胞培养自动化和远程实验

Jungmin Hamm, Seonghyeon Lim, Jiae Park, Jiwon Kang, Injun Lee, Yoongeun Lee, Jiseok Kang, Youngjun Jo, Jaejin Lee, Seoyeong Lee, M. C. Ratri, A. I. Brilian, Seungyeon Lee, Seokhwan Jeong, Kwanwoo Shin
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引用次数: 0

摘要

目前,机械臂已在各种环境中普遍使用,并将在实验室任务自动化方面发挥重要作用。然而,由于生物实验对研究人员的技能和经验等人为因素的依赖,其自动化仍具有挑战性。本文通过一个由机械臂、辅助工具和软件组成的模块化平台,介绍了适用于一般研究任务和生物研究任务的机器人自动化和远程控制。该平台有助于全自动或远程执行化学和生物学中的关键实验,包括液体处理、混合、细胞播种、培养和基因操作。机器人可与标准实验室设备无缝对接,并通过在线程序实时远程操作。通过机械臂网络摄像头集成的视觉系统可确保精确定位和物体定位,从而提高精确度。这种模块化机器人平台标志着实验室自动化的重大进步,与人类主导的实验相比,有望提高效率、可重复性和科学进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Modular Robotic Platform for Biological Research: Cell Culture Automation and Remote Experimentation
Robotic arms are now commonplace in diverse settings and are poised to play a crucial role in automating laboratory tasks. However, biological experiments remain challenging for automation due to their dependence on human factors, such as researchers’ skills and experience. This article introduces robotic automation and remote control for both general and biological research tasks through a modularized platform comprising a robotic arm, auxiliary tools, and software. This platform facilitates fully automated or remote execution of key experiments in chemistry and biology, including liquid handling, mixing, cell seeding, culturing, and genetic manipulation. The robot interfaces seamlessly with standard laboratory equipment and operates remotely in real time through an online program. Integration of a vision system via robotic arm webcams ensures precise positioning and object localization, enhancing accuracy. This modularized robotic platform signifies a substantial advancement in lab automation, promising enhanced efficiency, reproducibility, and scientific progress compared to human‐led experiments.
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