Assessing the Association between Neurocognitive Performance and Quality of Life in Individuals with Chronic Pain: A Cross-Sectional Study

Introduction: Chronic pain, a pervasive global health challenge, significantly impacts individuals' daily functioning and quality of life. This cross-sectional study explores the complex interplay between neurocognitive performance and quality of life in individuals experiencing chronic pain, recognizing the multifaceted nature of this phenomenon. Objectives Investigate the association between neurocognitive performance and chronic pain severity. Examine the relationship between neurocognitive deficits and different domains of quality of life in chronic pain. Methods: A diverse sample of 113 participants from Islamabad and Rawalpindi underwent correlational analysis. Neurocognitive performance was assessed using the Montreal Cognitive Assessment (MoCA), chronic pain severity was determined by pain history, and quality of life was measured using a validated scale. Demographic information was collected through an online survey. Results: The sample exhibited diversity in age, gender, and education. Pain history varied, with a majority reporting pain duration of 1-2 years. Neurocognitive performance, measured by MoCA, showed a mean score of 6.6 (±2.1), while the Quality of Life Scale yielded a mean score of 82 (±15). Correlation analysis revealed a weak negative association between neurocognitive performance and quality of life, though statistically non-significant (p = .279). Similarly, the correlation between pain history duration and neurocognitive performance was minimal and non-significant (p = .757). Conclusion: Contrary to expectations, the study did not find a significant correlation between neurocognitive performance and quality of life in individuals with chronic pain. The nuanced relationships observed highlight the complexity of chronic pain experiences, emphasizing the need for a comprehensive understanding that goes beyond the traditional pain-cognition paradigm. Tailored interventions should consider individual differences and address diverse cognitive and psychosocial factors, aiming to improve the overall well-being of those navigating the challenges of chronic pain.