CHANGES IN THE STATE OF IMMUNITY AT THE CELLULAR LEVEL IN PATIENTS WITH BRONCHIOLITIS

Acute bronchiolitis in children is considered one of the serious medical problems, since they occupy one of the leading places among the causes of childhood diseases. Despite numerous studies, the problem of acute bronchiolitis in frequently ill children remains unresolved, which is associated with delayed diagnosis, the peculiarities of the manifestation of clinical symptoms and laboratory data. The aim of the research is to study changes in immunity at the cellular level in patients with bronchiolitis. Materials and methods of research: to establish the relationship with immunity indicators at the cellular level, 62 patients with acute bronchiolitis were examined, divided into 2 groups: Group I - 31 patients with acute bronchiolitis in episodically ill children, group II - 31 patients with acute bronchiolitis in those who are often ill. Our study allows us to better understand the pathogenetic role of the immune status at the cellular level in the development of acute bronchiolitis in episodically ill and frequently ill children, for use in clinical practice and the development of more effective methods for predicting, diagnosing, and treating the disease