改用丁丙诺啡治疗慢性阿片类疼痛：使用三步低剂量递增剂量指南的病例系列

Q3 Medicine

Journal of opioid management Pub Date : 2024-02-08 DOI:10.5055/jom.0822

Gregory Acampora, Yi Zhang

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引用次数: 0

摘要

我们报告了马萨诸塞州总医院疼痛管理中心的 30 例系列病例，在这些病例中，我们采用了将慢性疼痛治疗从全激动阿片类药物 (FAO) 转换为丁丙诺啡 (BUP) 的指导原则。在这些患者中，有 24 人（80%）选择继续使用 BUP 而不是 FAO。有五名患者因副作用（疲劳）和/或疼痛未得到充分缓解而停止转换。一名患者在转换开始的当天选择不参加。没有发生重大不良事件。我们的结论是，应考虑将 BUP 转换为治疗慢性阿片类药物疼痛患者的替代方案。

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Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline

We report a 30-case series from the Pain Management Center at the Massachusetts General Hospital where we have applied a guideline to convert chronic treatment for pain from full agonist opioids (FAO) to buprenorphine (BUP). Of the patients, 24 (80 percent) elected to continue BUP over FAO. Five conversions were stopped for side effects (fatigue) and/or lack of sufficient pain reduction. One patient elected not to participate on the day that the conversion was to begin. There were no major adverse events. We conclude that conversion to BUP should be considered as an alternative to treat patients on chronic opioids for pain.

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来源期刊

Journal of opioid management Medicine-Anesthesiology and Pain Medicine

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： The Journal of Opioid Management deals with all aspects of opioids. From basic science, pre-clinical, clinical, abuse, compliance and addiction medicine, the journal provides and unbiased forum for researchers and clinicians to explore and manage the complexities of opioid prescription.