含含羞草叶提取物的速溶草药颊黏膜的制备与表征

Arpitha G, Dr. Anu Kaushik
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引用次数: 0

摘要

与传统剂型相比,颊膜具有明显的优势。药物可通过颊黏膜途径给药,避免了首次代谢,从而产生局部和全身作用。由于颊粘膜具有高渗透性和丰富的血液供应,因此药物吸收迅速。能通过这种途径给药的剂型很少。含羞草叶提取物具有多种药理作用。含羞草叶提取物的颊膜是通过溶剂浇铸法制备的,并对其特性进行了评估。共制备了六种配方,其中 F3 配方在 10 分钟内释放了 96.13% 的药物,是一种很有前景的配方。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fabrication and Characterization of Fast Dissolving Herbal Buccal Film Containing Mimosa Pudica Leaf Extract
Buccal films has distinct advantages over conventional dosage forms. Drugs can be delivered through buccal route, by avoiding first pass metabolism to produce local and systemic action. Rapid absorption of the drug is achieved because buccal mucosa is highly permeable with rich blood supply. Only few dosage forms are designed to deliver the drug through this route. Leaf extract of Mimosa pudica has number of pharmacological actions. Buccal film of leaf extract of mimosa pudica is prepared by solvent casting method and evaluated for its characteristics. Six formulations were prepared, out of which F3 formulation was found promising formulation, releases 96.13% of drug in 10 minutes.
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