开腹胆囊切除术后的长期死亡率和肠梗阻:系统回顾和元分析

IF 0.4 4区 医学 Q4 SURGERY
Sofie Anne-Marie Skovbo Jensen, Siv Fonnes, Anders Gram-Hanssen, Jacob Rosenberg
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引用次数: 0

摘要

开腹胆囊切除术后的长期结果在很大程度上是未知的。我们旨在调查开腹胆囊切除术后的长期死亡率和肠梗阻发生率。本系统综述和荟萃分析的报告遵循 PRISMA 2020 指南。研究方案已在 PROSPERO 注册(CRD42020178906)。我们于 2022 年 2 月在 PubMed、Embase 和 Cochrane CENTRAL 等数据库中检索了 n > 40、随访时间≥ 6 个月的长期并发症研究。结果包括死亡率和肠梗阻。进行了荟萃分析,结果以森林图的形式呈现。偏倚风险采用纽卡斯尔-渥太华量表或 Cochrane 偏倚风险工具 1 进行评估。我们纳入了 21 项研究。17项研究报告了开腹胆囊切除术后的长期死亡率,包括125222名患者,死亡率范围为0-35%。随访时间从六个月到十年不等。Meta 分析估计长期死亡率为 9.2%(95% CI 6.8-11.6)。一项有 90 名患者参加的研究报告了迷你腹腔镜手术,在 12 个月的随访期间无一人死亡。三项共有 66,257 名患者参与的研究报告了开腹胆囊切除术后肠梗阻的情况,发生率在 0.5% 至 2.6% 之间。随访时间从 36 个月到 67 个月不等。Meta 分析估计肠梗阻的长期发生率为 2.0% (95% CI 1.0-3.0)。随访 6 个月至 10 年后,长期死亡率为 9.2%,开腹胆囊切除术后 67 个月内的长期肠梗阻发生率为 2%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Long-term Mortality and Intestinal Obstruction after Open Cholecystectomy: A Systematic Review and Meta-analysis

Long-term Mortality and Intestinal Obstruction after Open Cholecystectomy: A Systematic Review and Meta-analysis

Long-term outcomes after open cholecystectomy are largely unknown. We aimed to investigate long-term mortality rate and incidence of intestinal obstruction after open cholecystectomy. Reporting of this systematic review and meta-analysis was according to the PRISMA 2020 guideline. A protocol was registered at PROSPERO (CRD42020178906). We searched the databases PubMed, Embase, and Cochrane CENTRAL in February 2022 for studies on long-term complications with n > 40 and follow-up ≥ 6 months. Outcomes included mortality and intestinal obstruction. Meta-analyses were conducted, and results were presented in forest plots. Risk of bias was assessed with the Newcastle–Ottawa Scale or Cochrane risk-of-bias tool 1. We included 21 studies. Long-term mortality after open cholecystectomy was reported in 17 studies including 125,222 patients, and it ranged from 0–35%. Follow-up ranged from six months to ten years. Meta-analysis estimated a long-term mortality rate of 9.2% (95% CI 6.8–11.6). One study with 90 patients reported on mini-laparotomy and none died during the 12 months follow-up. Three studies with 66,257 patients reported on intestinal obstruction after open cholecystectomy with an incidence ranging from 0.5% to 2.6%. Follow-up ranged from 36 to 67 months. Meta-analysis estimated a long-term rate of intestinal obstruction of 2.0% (95% CI 1.0–3.0). After a follow-up of six months to ten years, long-term mortality was 9.2%, and long-term incidence of intestinal obstruction was 2% up to 67 months after open cholecystectomy.

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来源期刊
CiteScore
0.60
自引率
25.00%
发文量
412
审稿时长
6-12 weeks
期刊介绍: The Indian Journal of Surgery is the official publication of the Association of Surgeons of India that considers for publication articles in all fields of surgery. Issues are published bimonthly in the months of February, April, June, August, October and December. The journal publishes Original article, Point of technique, Review article, Case report, Letter to editor, Teachers and surgeons from the past - A short (up to 500 words) bio sketch of a revered teacher or surgeon whom you hold in esteem and Images in surgery, surgical pathology, and surgical radiology. A trusted resource for peer-reviewed coverage of all types of surgery Provides a forum for surgeons in India and abroad to exchange ideas and advance the art of surgery The official publication of the Association of Surgeons of India 92% of authors who answered a survey reported that they would definitely publish or probably publish in the journal again The Indian Journal of Surgery offers peer-reviewed coverage of all types of surgery. The Journal publishes Original articles, Points of technique, Review articles, Case reports, Letters, Images and brief biographies of influential teachers and surgeons. The Journal spans General Surgery, Pediatric Surgery, Neurosurgery, Plastic Surgery, Cardiothoracic Surgery, Vascular Surgery, Rural Surgery, Orthopedic Surgery, Urology, Surgical Oncology, Radiology, Anaesthesia, Trauma Services, Minimal Access Surgery, Endocrine Surgery, GI Surgery, ENT, Colorectal Surgery, surgical practice and research. The Journal provides a forum for surgeons from India and abroad to exchange ideas, to propagate the advancement of science and the art of surgery and to promote friendship among surgeons in India and abroad. This has been a trusted platform for surgons in communicating up-to-date scientific informeation to the community.
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