Seth L. Sherman M.D. , Neil Askew M.Sc. , Leo M. Nherera Ph.D. , Richard J. Searle Ph.D. , David C. Flanigan M.D.
{"title":"全缝合半月板修复技术与半月板部分切除术治疗水平裂缝撕裂相比具有成本效益","authors":"Seth L. Sherman M.D. , Neil Askew M.Sc. , Leo M. Nherera Ph.D. , Richard J. Searle Ph.D. , David C. Flanigan M.D.","doi":"10.1016/j.asmr.2023.100847","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p>To determine the cost-effectiveness of meniscal repair (MR) using an all-suture–based technique when compared to partial meniscectomy (PM) for horizontal cleavage tears (HCTs) from a payor’s perspective in the United States.</p></div><div><h3>Methods</h3><p>A state-transition model and cost-utility analysis were developed from a US payor’s perspective to project treatment costs and quality-adjusted life-years (QALYs) in a cohort of 35-year-old patients without osteoarthritis at baseline and presenting with either a lateral or medial HCT. Two outpatient costing perspectives were used, namely ambulatory surgical centers (ASCs) and hospitals. The state-transition model had 7 health states with transition probabilities, costs, and utilities obtained from the existing literature. Cost-effectiveness was assessed using a willingness-to-pay threshold of $100,000/QALY, and sensitivity analysis considered the effects of parameter uncertainty on model results. MR failure rates were focused on an all-suture–based technique; however, in a separate scenario, this study considered effectiveness data from various MR techniques and devices.</p></div><div><h3>Results</h3><p>MR dominated PM over a lifetime horizon, increasing QALYs by 0.43 per patient and decreasing the cost by $12,227 per patient within a hospital setting (and by $12,570 within an ASC). MR with an all-suture–based technique continued to be the dominant treatment when age at primary treatment was varied between 30 and 60 years. Sensitivity analysis showed that MR was not cost-effective in year 1, was cost-effective from year 2, and was cost-saving from year 6 onward from both ASC and hospital perspectives. Probabilistic sensitivity analysis found that MR was cost-effective over a lifetime horizon in 99% of 10,000 iterations on base-case analysis.</p></div><div><h3>Conclusions</h3><p>Using a lifetime horizon, this study found that from a payor’s perspective, MR is a cost-saving intervention when compared with PM in patients with an HCT.</p></div><div><h3>Level of Evidence</h3><p>Level III, economic analysis.</p></div>","PeriodicalId":34631,"journal":{"name":"Arthroscopy Sports Medicine and Rehabilitation","volume":"6 2","pages":"Article 100847"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666061X23001980/pdfft?md5=70342cde14a2ae0deb821c8ae9672ff5&pid=1-s2.0-S2666061X23001980-main.pdf","citationCount":"0","resultStr":"{\"title\":\"An All-Suture–Based Technique for Meniscal Repair Is Cost-Effective in Comparison to Partial Meniscectomy for Horizontal Cleavage Tears\",\"authors\":\"Seth L. Sherman M.D. , Neil Askew M.Sc. , Leo M. Nherera Ph.D. , Richard J. Searle Ph.D. , David C. Flanigan M.D.\",\"doi\":\"10.1016/j.asmr.2023.100847\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><p>To determine the cost-effectiveness of meniscal repair (MR) using an all-suture–based technique when compared to partial meniscectomy (PM) for horizontal cleavage tears (HCTs) from a payor’s perspective in the United States.</p></div><div><h3>Methods</h3><p>A state-transition model and cost-utility analysis were developed from a US payor’s perspective to project treatment costs and quality-adjusted life-years (QALYs) in a cohort of 35-year-old patients without osteoarthritis at baseline and presenting with either a lateral or medial HCT. Two outpatient costing perspectives were used, namely ambulatory surgical centers (ASCs) and hospitals. The state-transition model had 7 health states with transition probabilities, costs, and utilities obtained from the existing literature. Cost-effectiveness was assessed using a willingness-to-pay threshold of $100,000/QALY, and sensitivity analysis considered the effects of parameter uncertainty on model results. MR failure rates were focused on an all-suture–based technique; however, in a separate scenario, this study considered effectiveness data from various MR techniques and devices.</p></div><div><h3>Results</h3><p>MR dominated PM over a lifetime horizon, increasing QALYs by 0.43 per patient and decreasing the cost by $12,227 per patient within a hospital setting (and by $12,570 within an ASC). MR with an all-suture–based technique continued to be the dominant treatment when age at primary treatment was varied between 30 and 60 years. Sensitivity analysis showed that MR was not cost-effective in year 1, was cost-effective from year 2, and was cost-saving from year 6 onward from both ASC and hospital perspectives. Probabilistic sensitivity analysis found that MR was cost-effective over a lifetime horizon in 99% of 10,000 iterations on base-case analysis.</p></div><div><h3>Conclusions</h3><p>Using a lifetime horizon, this study found that from a payor’s perspective, MR is a cost-saving intervention when compared with PM in patients with an HCT.</p></div><div><h3>Level of Evidence</h3><p>Level III, economic analysis.</p></div>\",\"PeriodicalId\":34631,\"journal\":{\"name\":\"Arthroscopy Sports Medicine and Rehabilitation\",\"volume\":\"6 2\",\"pages\":\"Article 100847\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666061X23001980/pdfft?md5=70342cde14a2ae0deb821c8ae9672ff5&pid=1-s2.0-S2666061X23001980-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arthroscopy Sports Medicine and Rehabilitation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666061X23001980\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arthroscopy Sports Medicine and Rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666061X23001980","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
An All-Suture–Based Technique for Meniscal Repair Is Cost-Effective in Comparison to Partial Meniscectomy for Horizontal Cleavage Tears
Purpose
To determine the cost-effectiveness of meniscal repair (MR) using an all-suture–based technique when compared to partial meniscectomy (PM) for horizontal cleavage tears (HCTs) from a payor’s perspective in the United States.
Methods
A state-transition model and cost-utility analysis were developed from a US payor’s perspective to project treatment costs and quality-adjusted life-years (QALYs) in a cohort of 35-year-old patients without osteoarthritis at baseline and presenting with either a lateral or medial HCT. Two outpatient costing perspectives were used, namely ambulatory surgical centers (ASCs) and hospitals. The state-transition model had 7 health states with transition probabilities, costs, and utilities obtained from the existing literature. Cost-effectiveness was assessed using a willingness-to-pay threshold of $100,000/QALY, and sensitivity analysis considered the effects of parameter uncertainty on model results. MR failure rates were focused on an all-suture–based technique; however, in a separate scenario, this study considered effectiveness data from various MR techniques and devices.
Results
MR dominated PM over a lifetime horizon, increasing QALYs by 0.43 per patient and decreasing the cost by $12,227 per patient within a hospital setting (and by $12,570 within an ASC). MR with an all-suture–based technique continued to be the dominant treatment when age at primary treatment was varied between 30 and 60 years. Sensitivity analysis showed that MR was not cost-effective in year 1, was cost-effective from year 2, and was cost-saving from year 6 onward from both ASC and hospital perspectives. Probabilistic sensitivity analysis found that MR was cost-effective over a lifetime horizon in 99% of 10,000 iterations on base-case analysis.
Conclusions
Using a lifetime horizon, this study found that from a payor’s perspective, MR is a cost-saving intervention when compared with PM in patients with an HCT.