植物合成纳米粒子增强生物活性材料机械性能的比较评估:体外研究。

Pub Date : 2023-10-01 Epub Date: 2023-12-19 DOI:10.4103/ccd.ccd_140_23
Harshita Lath, Gaurav Patri, Atul Anand Bajoria, Aanchal Banka
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引用次数: 0

摘要

目的:本研究旨在评估和比较添加了植物合成纳米二氧化钛(nTiO2)和纳米姜黄素(nCur)的ACTIVA生物活性基底/衬垫(ABBL)的机械性能:制备了 30 个 ABBL(第 1 组)、ABBL + nTiO2(第 2 组)和 ABBL + nCur(第 3 组)样品,用于测试抗压强度(CS)和抗弯强度(FS)。制作了 45 个圆柱体(每组 15 个)(6 毫米 × 4 毫米)用于 CS 测量,45 个用于三点弯曲 FS 测量(22 毫米 × 2 毫米 × 2 毫米)。在万能试验机上进行测试,CS 测试的十字头速度为 0.5 毫米/分钟,FS 测量的十字头速度为 0.5 毫米/分钟,两个支撑之间的间距为 20 毫米:CS 和 FS 的组间比较采用单因素方差分析进行评估。显著性水平设定为 0.05:结果:组间比较显示出整体显著差异(CS:P = 0.016)和(FS:P = 0.001),其中第 1 组强度最高,第 3 组强度最低。第 1 组和第 2 组之间无明显差异,而第 3 组与第 1 组相比强度明显较低:结论:ABBL + 3% nTiO2 的机械性能下降不明显,而 ABBL + 7% nCur 的机械性能下降明显。
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Comparative Evaluation of the Mechanical Properties of a Bioactive Material Enhanced by Phytosynthesized Nanoparticles: An In vitro Study.

Aims: The aim was the study was to evaluate and compare the mechanical properties of ACTIVA Bioactive Base/Liner (ABBL) enhanced with phytosynthesized titanium dioxide nanoparticles (nTiO2) and nano-curcumin (nCur).

Methodology: Thirty samples each of ABBL (Group 1), ABBL + nTiO2 (Group 2), and ABBL + nCur (Group 3) were prepared for testing the compressive strength (CS) and flexural strength (FS). Forty-five cylinders (15 per group) (6 mm × 4 mm) were fabricated for CS and 45 for three-point bending FS measurements (22 mm × 2 mm × 2 mm). They were tested in a universal testing machine at a crosshead speed of 0.5 mm/min for CS and 0.5 mm/min with 20 mm space between the two supports for FS measurements.

Statistical analysis: Intergroup comparison of CS and FS was assessed using one-way ANOVA. The level of significance was set at 0.05.

Results: Intergroup comparison showed an overall significant difference (P = 0.016 for CS) and (P = 0.001 for FS), where Group 1 had the highest and Gr 3 the least strength. No significant difference was observed between Group 1 and Group 2, while Group 3 showed significantly low strength when compared to Group 1.

Conclusions: ABBL + 3% nTiO2 showed nonsignificant decrease while ABBL + 7% nCur showed significant decrease in mechanical properties.

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