Billingsley Kaambwa, Taylor-Jade Woods, Andrea Natsky, Norma Bulamu, Christine Mpundu-Kaambwa, Kelly A Loffler, Alexander Sweetman, Peter G Catcheside, Amy C Reynolds, Robert Adams, Danny J Eckert
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Knowledge of the content and concepts covered by specific QoL instruments is essential to determine which instruments are best suited for conducting economic evaluations of sleep-related interventions.</p><p><strong>Objectives: </strong>This review aims to identify the QoL instruments that have been applied in economic evaluations of sleep disorder interventions and compare their conceptual overlap and content coverage using the framework of the International Classification of Functioning, Disability and Health (ICF).</p><p><strong>Methods: </strong>A systematic review of full economic evaluations in sleep published in peer-reviewed journals from conception to 30 May, 2023 was conducted. MEDLINE, PsychInfo, ProQuest, Cochrane, Scopus, CINAHL, Web of Science and Emcare were searched for eligible studies. Studies incorporating either generic or sleep-specific QoL instruments as the primary or secondary measures of effectiveness within a full economic evaluation were included. Quality appraisal against the JBI Critical Appraisal Checklist for Economic Evaluations and EURONHEED checklists and mapping of QoL items to ICF categories were performed by two reviewers, with a third helping settle any potential differences.</p><p><strong>Results: </strong>Sixteen instruments were identified as having been used in sleep health economic evaluations. The EQ-5D-3L, Epworth Sleepiness Scale, and Insomnia Severity Index were the most widely used, but the latter two are predominantly diagnostic tools and not specifically designed to guide economic evaluations. Other instruments with broader ICF content coverage have been least used, and these include the Sleep Apnea Quality of Life Index, Functional Outcomes of Sleep Questionnaire, 15 Dimensions, Short-Form 6 Dimensions, 12-item Short Form Survey, 36-item Short Form Survey and the GRID Hamilton Rating Scale for Depression.</p><p><strong>Conclusions: </strong>This study provides an overview of current QoL instruments used in economic evaluations of sleep with respect to their content coverage. 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引用次数: 0
摘要
背景：使用调查问卷对睡眠障碍患者的生活质量（QoL）进行评估对于比较干预措施的益处十分必要。了解特定 QoL 工具所涵盖的内容和概念对于确定哪些工具最适合对睡眠相关干预措施进行经济评估至关重要：本综述旨在确定已应用于睡眠障碍干预措施经济评估的 QoL 工具，并使用国际功能、残疾和健康分类（ICF）框架比较其概念重叠和内容覆盖：方法：对自概念提出至 2023 年 5 月 30 日期间在同行评审期刊上发表的有关睡眠的完整经济评价进行了系统回顾。在 MEDLINE、PsychInfo、ProQuest、Cochrane、Scopus、CINAHL、Web of Science 和 Emcare 中检索了符合条件的研究。纳入了将通用或睡眠特异性 QoL 工具作为全面经济评估中的主要或次要有效性衡量标准的研究。由两名审稿人根据JBI经济评价关键评估检查表和EURONHEED检查表进行质量评估，并将QoL项目映射到ICF类别，第三名审稿人帮助解决任何潜在的分歧：结果：共发现 16 种工具曾用于睡眠健康经济评估。EQ-5D-3L、埃普沃斯嗜睡量表和失眠严重程度指数使用最为广泛，但后两者主要是诊断工具，并非专门用于指导经济评估。其他 ICF 内容覆盖面更广的工具使用最少，其中包括睡眠呼吸暂停生活质量指数、睡眠功能结果问卷、15 个维度、6 个维度短表、12 项短表调查、36 项短表调查和 GRID 汉密尔顿抑郁评分量表：本研究概述了目前用于睡眠经济评估的 QoL 工具的内容覆盖范围。建议在此类评估中结合使用通用工具和针对睡眠的工具，并扩大《国际功能、残疾和健康分类》的内容覆盖面。
Content Comparison of Quality-of-Life Instruments Used in Economic Evaluations of Sleep Disorder Interventions: A Systematic Review.
Background: Assessment of quality of life (QoL) in people living with sleep disorders using questionnaires is necessary to compare intervention benefits. Knowledge of the content and concepts covered by specific QoL instruments is essential to determine which instruments are best suited for conducting economic evaluations of sleep-related interventions.
Objectives: This review aims to identify the QoL instruments that have been applied in economic evaluations of sleep disorder interventions and compare their conceptual overlap and content coverage using the framework of the International Classification of Functioning, Disability and Health (ICF).
Methods: A systematic review of full economic evaluations in sleep published in peer-reviewed journals from conception to 30 May, 2023 was conducted. MEDLINE, PsychInfo, ProQuest, Cochrane, Scopus, CINAHL, Web of Science and Emcare were searched for eligible studies. Studies incorporating either generic or sleep-specific QoL instruments as the primary or secondary measures of effectiveness within a full economic evaluation were included. Quality appraisal against the JBI Critical Appraisal Checklist for Economic Evaluations and EURONHEED checklists and mapping of QoL items to ICF categories were performed by two reviewers, with a third helping settle any potential differences.
Results: Sixteen instruments were identified as having been used in sleep health economic evaluations. The EQ-5D-3L, Epworth Sleepiness Scale, and Insomnia Severity Index were the most widely used, but the latter two are predominantly diagnostic tools and not specifically designed to guide economic evaluations. Other instruments with broader ICF content coverage have been least used, and these include the Sleep Apnea Quality of Life Index, Functional Outcomes of Sleep Questionnaire, 15 Dimensions, Short-Form 6 Dimensions, 12-item Short Form Survey, 36-item Short Form Survey and the GRID Hamilton Rating Scale for Depression.
Conclusions: This study provides an overview of current QoL instruments used in economic evaluations of sleep with respect to their content coverage. A combination of generic and sleep-specific instruments with broader ICF content coverage is recommended for such evaluations.
期刊介绍：
PharmacoEconomics is the benchmark journal for peer-reviewed, authoritative and practical articles on the application of pharmacoeconomics and quality-of-life assessment to optimum drug therapy and health outcomes. An invaluable source of applied pharmacoeconomic original research and educational material for the healthcare decision maker.
PharmacoEconomics is dedicated to the clear communication of complex pharmacoeconomic issues related to patient care and drug utilization.
PharmacoEconomics offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content. Each article is accompanied by a Key Points summary, giving a time-efficient overview of the content to a wide readership. Articles may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand the scientific content and overall implications of the article.
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