Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Ben Goldacre, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian MacKenna, Sarah Finer
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Adults with T2D lost weight overall (median δ = -0.1 kg/m<sup>2</sup>/year [interquartile range {IQR} -0.7-0.4]). However, rapid weight gain was common (20.7%) and associated with the following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} = 0.77 to 0.79]); age (older age reduced odds, for example, aged 60-69 years versus 18-29 years: aOR 0.66 [95% CI = 0.61 to 0.71]); deprivation (least deprived Index of Multiple Deprivation [IMD] quintile versus most deprived IMD quintile: aOR 0.87 [95% CI = 0.85 to 0.89]); White ethnicity (Black versus White: aOR 0.95 [95% CI = 0.92 to 0.98]); mental health conditions (for example, depression: aOR 1.13 [95% CI = 1.12 to 1.15]); and diabetes treatment (non-insulin treatment versus no pharmacological treatment: aOR 0.68 [95% CI = 0.67 to 0.69]). Adults with hypertension maintained stable weight overall (median δ = 0.0 kg/m<sup>2</sup>/year [IQR -0.6-0.5]); however, rapid weight gain was common (24.7%) and associated with similar characteristics as in T2D.</p><p><strong>Conclusion: </strong>Among adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common among females, younger adults, those living in more deprived areas, and those with mental health conditions.</p>","PeriodicalId":55320,"journal":{"name":"British Journal of General Practice","volume":" ","pages":"e767-e776"},"PeriodicalIF":5.3000,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466294/pdf/","citationCount":"0","resultStr":"{\"title\":\"Weight trends among adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY.\",\"authors\":\"Miriam Samuel, Robin Y Park, Sophie V Eastwood, Fabiola Eto, Caroline E Morton, Daniel Stow, Sebastian Bacon, Ben Goldacre, Amir Mehrkar, Jessica Morley, Iain Dillingham, Peter Inglesby, William J Hulme, Kamlesh Khunti, Rohini Mathur, Jonathan Valabhji, Brian MacKenna, Sarah Finer\",\"doi\":\"10.3399/BJGP.2023.0492\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>COVID-19 pandemic restrictions may have influenced behaviours related to weight.</p><p><strong>Aim: </strong>To describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.</p><p><strong>Design and setting: </strong>An observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.</p><p><strong>Method: </strong>Clinical and sociodemographic characteristics associated with rapid weight gain (>0.5 kg/m<sup>2</sup>/year) were investigated using multivariable logistic regression.</p><p><strong>Results: </strong>Data were extracted on adults with T2D (<i>n</i> = 1 231 455, 43.9% female, and 76.0% White British) or hypertension (<i>n</i> = 3 558 405, 49.7% female, and 84.3% White British). 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引用次数: 0
摘要
背景：目的：描述 COVID-19 大流行期间英格兰 2 型糖尿病 (T2D) 和/或高血压患者的体重变化模式。设计与背景：经英格兰国家医疗服务系统（NHS）批准，我们利用通过 TPP 内的 OpenSAFELY 服务获取的例行收集的约 40% 的英格兰成人健康数据开展了一项观察性队列研究：我们使用多变量逻辑回归法调查了与体重快速增长（>0-5kg/m2/年）相关的临床和社会人口特征：我们提取了患有 T2D（人数=1,231,455，44%为女性，76%为英国白人）或高血压（人数=3,558,405，50%为女性，84%为英国白人）的成年人的数据。患有 T2D 的成年人总体体重减轻（中位数 δ = -0.1kg/m2/年 [IQR: -0.7，0.4]），但体重增加过快的情况很常见（20.7%），且与性别（男性 vs 女性：aOR 0.78[95%CI 0.77，0.79]）、年龄有关，年龄越大，几率越低（例如，60-69 岁 vs 18-29 岁：aOR 0.66[0.61, 0.71]）；贫困程度，贫困程度越高，几率越低（例如，60-69 岁 vs 18-29 岁：aOR 0.66[0.61, 0.71]）。71]）；贫困程度（最贫困-IMD vs 最贫困-IMD：aOR 0.87[0.85，0.89]）；白人种族（黑人 vs 白人：aOR 0.95[0.92，0.98]）；精神健康状况（如抑郁症：aOR 1.13 [1.12，1.15]）；以及糖尿病治疗（非胰岛素治疗 vs 无药物治疗：aOR 0.68[0.67，0.69]）。患有高血压的成年人总体体重保持稳定（中位数δ=0.0kg/m2/年[-0.6，0.5]），但体重迅速增加的情况很常见（24.7%），其相关特征与T2D相似：结论：在英格兰，患有终末期糖尿病和/或高血压的成年人中，女性、年轻成年人、生活在较贫困地区的人以及患有精神疾病的人体重快速增长的现象更为普遍。
Weight trends among adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY.
Background: COVID-19 pandemic restrictions may have influenced behaviours related to weight.
Aim: To describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.
Design and setting: An observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.
Method: Clinical and sociodemographic characteristics associated with rapid weight gain (>0.5 kg/m2/year) were investigated using multivariable logistic regression.
Results: Data were extracted on adults with T2D (n = 1 231 455, 43.9% female, and 76.0% White British) or hypertension (n = 3 558 405, 49.7% female, and 84.3% White British). Adults with T2D lost weight overall (median δ = -0.1 kg/m2/year [interquartile range {IQR} -0.7-0.4]). However, rapid weight gain was common (20.7%) and associated with the following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} = 0.77 to 0.79]); age (older age reduced odds, for example, aged 60-69 years versus 18-29 years: aOR 0.66 [95% CI = 0.61 to 0.71]); deprivation (least deprived Index of Multiple Deprivation [IMD] quintile versus most deprived IMD quintile: aOR 0.87 [95% CI = 0.85 to 0.89]); White ethnicity (Black versus White: aOR 0.95 [95% CI = 0.92 to 0.98]); mental health conditions (for example, depression: aOR 1.13 [95% CI = 1.12 to 1.15]); and diabetes treatment (non-insulin treatment versus no pharmacological treatment: aOR 0.68 [95% CI = 0.67 to 0.69]). Adults with hypertension maintained stable weight overall (median δ = 0.0 kg/m2/year [IQR -0.6-0.5]); however, rapid weight gain was common (24.7%) and associated with similar characteristics as in T2D.
Conclusion: Among adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common among females, younger adults, those living in more deprived areas, and those with mental health conditions.
期刊介绍：
The British Journal of General Practice is an international journal publishing research, editorials, debate and analysis, and clinical guidance for family practitioners and primary care researchers worldwide.
BJGP began in 1953 as the ‘College of General Practitioners’ Research Newsletter’, with the ‘Journal of the College of General Practitioners’ first appearing in 1960. Following the change in status of the College, the ‘Journal of the Royal College of General Practitioners’ was launched in 1967. Three editors later, in 1990, the title was changed to the ‘British Journal of General Practice’. The journal is commonly referred to as the ''BJGP'', and is an editorially-independent publication of the Royal College of General Practitioners.
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