新生儿皮肤黑色素瘤伴皮肤转移:病例报告和文献综述。

IF 1.5 4区 医学 Q3 DERMATOLOGY
Melanoma Research Pub Date : 2024-04-01 Epub Date: 2024-02-07 DOI:10.1097/CMR.0000000000000956
Alp Ercan, Can Ege Yalçin
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引用次数: 0

摘要

恶性黑色素瘤是一种罕见的儿童皮肤癌,主要影响 10 岁以上的儿童。约有 1%的新生儿患有先天性巨痣,这增加了患病风险。然而,在新生儿期被确诊的先天性巨痣发展成黑色素瘤的情况却异常罕见。我们介绍了一例新生儿先天性黑色素瘤病例,患者背部原有的痣上长出了结节。我们回顾了有关处理此类病例的文献。该病例强调了考虑先天性痣恶性转化的重要性以及治疗中的挑战。由于 80 年来报告的病例有限,很难提供有关存活率和治疗方案的结论性结论。临床医生应报告结果,以制定新生儿黑色素瘤的管理算法。我们需要开展进一步的研究,以加深对先天性巨型毛痣及相关黑色素瘤患者的病因和治疗方法的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neonatal cutaneous melanoma with cutaneous metastasis: a case report and review of literature.

Malignant melanoma, a rare skin cancer in children, primarily affects individuals over 10 years old. Giant congenital nevi, found in about 1% of newborns, increases the risk. However, the development of melanoma from a pre-existing giant congenital nevus diagnosed during the neonatal period is exceptionally rare. We present a case of congenital melanoma in a newborn, where nodules grew on an existing nevus on the baby's back. Literature on managing such cases was reviewed. This case highlights the importance of considering malignant transformation in congenital nevi and the challenges in their management. Due to limited reported cases over 80 years, conclusive findings on survival and treatment options are difficult to provide. Clinicians should report outcomes to develop a management algorithm for neonatal melanoma. Further studies are needed to enhance understanding of causes and treatment for patients with congenital giant hairy nevi and associated melanoma.

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来源期刊
Melanoma Research
Melanoma Research 医学-皮肤病学
CiteScore
3.40
自引率
4.50%
发文量
139
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Melanoma Research is a well established international forum for the dissemination of new findings relating to melanoma. The aim of the Journal is to promote the level of informational exchange between those engaged in the field. Melanoma Research aims to encourage an informed and balanced view of experimental and clinical research and extend and stimulate communication and exchange of knowledge between investigators with differing areas of expertise. This will foster the development of translational research. The reporting of new clinical results and the effect and toxicity of new therapeutic agents and immunotherapy will be given emphasis by rapid publication of Short Communications. ​Thus, Melanoma Research seeks to present a coherent and up-to-date account of all aspects of investigations pertinent to melanoma. Consequently the scope of the Journal is broad, embracing the entire range of studies from fundamental and applied research in such subject areas as genetics, molecular biology, biochemistry, cell biology, photobiology, pathology, immunology, and advances in clinical oncology influencing the prevention, diagnosis and treatment of melanoma.
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