由苯乙烯/乙烯/丁烯和聚氨酯制成的输尿管双 J 支架在植入前后的结壳情况。

IF 0.8 4区 医学 Q4 BIOPHYSICS
Adam Haliński, Kamila Pasik, Andrzej Haliński, Alberto Trinchieri, Noor Buchholz, Katarzyna Arkusz
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引用次数: 0

摘要

目的:本研究旨在确定输尿管肾镜碎石术(URS-L)后输尿管双 J 支架(DJ 支架)上晶体、结石和生物膜沉积的亲和力。分析从两个方面进行:确定用于制造输尿管支架的哪种材料会促进结石沉积,以及 DJ 支架的哪个部位最容易发生堵塞:本研究纳入了 120 名留置 DJ 支架时间在 7 到 78 天之间的患者。用扫描电子显微镜(SEM)观察了 DJ 支架的结壳情况,并用标准的 MTS Micro Bionix 拉伸试验检测了 DJ 支架的机械性能:研究结果表明,聚氨酯导管的结壳亲和力远高于苯乙烯/乙烯/丁烯嵌段共聚物。研究结果表明,近端(肾盂)和远端(膀胱)部分最容易出现 URS-L 后碎片和尿素盐沉积。即使在植入 7 天后,DJ 输尿管支架的外表面和内表面仍被完全覆盖:所做分析表明,与硅基共聚物相比,聚氨酯 DJ 支架对结石和氯化钠结晶沉积的亲和力要高得多。输尿管支架的表面需要改进,以尽量减少盐分和肾结石沉积,从而减少生物膜的形成以及缺陷和裂缝的出现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Encrustation of the ureteral double-J Stents made of styrene/ethylene/butylene and polyurethane before and after implantation.

Purpose: The aim of this study was to determine the affinity to crystal, calculi and biofilm deposition on ureteral double-J stents (DJ stents) after ureterorenoscopic-lithotripsy procedure (URS-L). The analysis was performed in two aspects: to determine which material used for fabricating ureteral stents promotes encrustation and which part of the DJ stents is the most vulnerable for blockage.

Methods: One hundred and twenty patients with an indwelling DJ stent duration between 7 and 78 days were included in this study. The encrustation of DJ stents was characterized by scanning electron microscopy (SEM), and the mechanical properties of DJ stents were examined using the standard MTS Micro Bionix tensile test.

Results: This study showed that polyurethane catheters have a much higher affinity for encrustation than styrene/ethylene/butylene block copolymer. Obtained results indicated the proximal (renal pelvis) and distal (urinary bladder) part is the most susceptible to post-URS-L fragments and urea salt deposition. Both the DJ ureteral stents' outer and inner surfaces were completely covered even after 7 days of implantation.

Conclusions: Performed analysis pointed out that polyurethane DJ stents have a much higher affinity for encrustation of calculi and NaCl crystals compared to the silicone-based copolymer. The surface of the ureteral stents needs improvement to minimize salt and kidney stone deposition, causing pre-biofilm formation and the occurrence of defects and cracks.

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来源期刊
Acta of bioengineering and biomechanics
Acta of bioengineering and biomechanics BIOPHYSICS-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
10.00%
发文量
0
期刊介绍: Acta of Bioengineering and Biomechanics is a platform allowing presentation of investigations results, exchange of ideas and experiences among researchers with technical and medical background. Papers published in Acta of Bioengineering and Biomechanics may cover a wide range of topics in biomechanics, including, but not limited to: Tissue Biomechanics, Orthopedic Biomechanics, Biomaterials, Sport Biomechanics.
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