A 型主动脉夹层患者术前病情严重是否是主动脉瓣保留再植术的禁忌症?

Joël Lapeze, Jacques Robin, Jean Ninet, Jean-François Obadia, Fadi Farhat
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摘要

背景:A 型主动脉夹层(TAAD)的手术治疗仍存在争议。本研究旨在证明在 92 例连续接受主动脉瓣根部重建术(AVSR)的 TAAD 患者中,即使术前情况严重(灌注不良、休克或两者兼有),主动脉瓣根部重建术的可行性和安全性:我们对医院数据库进行了审查,以确定 14 年来因 TAAD 而接受 AVSR 手术的所有患者。结果:年龄(61±13 岁)、血压、心率、血氧饱和度、心率、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度、血氧饱和度结果:收集了年龄(61±13 岁)、Logistic Euroscore(23.4±15.3%)、交叉钳夹时间(113±39 分钟)、心肺旁路时间(142±49 分钟)和循环停止时间(22±13 分钟)。住院死亡率为 16.3%。平均随访时间为 27.6 个月。一名患者因主动脉瓣关闭不全而提前再次手术。1年的精算存活率为82.5%。对每组患者的分析表明,他们的死亡率和发病率相当:根据我们治疗 TAAD 的经验,无论术前有无灌注不良或休克,都可以进行再植手术,术后死亡率或发病率均可接受。需要提醒的是,70 岁以上的患者要慎重。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is a severe preoperative condition a contraindication for aortic valve-sparing reimplantation in type A aortic dissection?

Background: Type A aortic dissection (TAAD) surgical management is still under debate. The purpose of this study was to demonstrate the feasibility and safety of the aortic valve-sparing root reconstruction (AVSR) procedure in 92 consecutive patients operated for TAAD, even when preoperative condition was severe (malperfusion, shock or both).

Methods: Our hospital database was reviewed to identify all patients who underwent an AVSR procedure for TAAD over 14 years. From May 2000 to June 2014, 92 consecutive patients were studied regarding to their preoperative condition.

Results: Age (61±13 years) and logistic Euroscore (23.4±15.3%) as well as cross-clamping (113±39 min), cardiopulmonary bypass (142±49 min) and circulatory arrest (22±13 min) times were collected. Hospital mortality was 16.3%. Mean follow-up was complete for a mean period of 27.6 months. One patient had early reoperation for aortic insufficiency. Actuarial survival at 1 year was 82.5%. The analysis of each group showed comparable mortality and morbidity in between patients.

Conclusions: Based upon our experience in the management of TAAD, a reimplantation procedure could be performed regardless preoperative malperfusion or shock, with an acceptable postoperative over mortality or morbidity. A word of caution should be brought to patients over 70 years old.

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