灌注压与脑死亡组织学：靠生命维持系统维持生命的婴儿的独特病例。

IF 1.3 4区医学 Q3 PATHOLOGY

Pediatric and Developmental Pathology Pub Date : 2024-07-01 Epub Date: 2024-01-30 DOI:10.1177/10935266231223276

Meagan Chambers, Gail Deutsch

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引用次数: 0

摘要

脑死亡在成人和儿童中并不少见。大多数病例在宣布脑死亡后很快就会脱离生命支持系统。较少见的情况是，在神经功能停止后，通过生命支持系统维持全身灌注一段时间。这些病例提供了罕见的机会，让我们可以在整体缺氧缺血性损伤的背景下探索坏死和自溶的组织学。在此，我们描述了一个不寻常的病例，该婴儿在宣布脑死亡后依靠生命支持维持了 2 周，重点是由此产生的大体和组织学结果，包括对其潜在生理学的讨论。

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Perfusion Pressure and the Histology of Brain Death: A Unique Case in an Infant Maintained on Life Support.

Brain death is a not uncommon phenomena in the adult and pediatric population. Most cases are removed from life support soon after brain death is declared. Less commonly, systemic perfusion is maintained by life support for some time after neurologic function stops. These cases present uncommon opportunities to explore the histology of necrosis and autolysis in the context of global hypoxic ischemic damage. Here, we describe the unusual case of an infant maintained on life support for 2 weeks after brain death was declared with an emphasis on the resulting gross and histologic findings including a discussion of their underlying physiology.

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来源期刊

Pediatric and Developmental Pathology 医学-病理学

CiteScore

3.70

自引率

5.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information.