对接受血液透析的住院患者在药剂师指导下实施标准化给药时间的评估。

IF 2.3 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Annals of Pharmacotherapy Pub Date : 2024-10-01 Epub Date: 2024-01-31 DOI:10.1177/10600280231220079
Abbie L Blunier, Megan R Cheatham, Karishma S Deodhar, Christopher A Geik, Todd A Walroth, Jessica A Whitten, Christie M Davis
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引用次数: 0

摘要

背景:漏服药物是一种常见的、通常可以预防的用药相关错误,与住院时间延长和死亡率升高有关。血液透析是一种常见且相对可预测的原因,患者无法进行血液透析,从而导致漏服药物:目的:评估由药剂师主导的干预措施的影响,该措施旨在规范需要进行血液透析且处方为抗高血压药、抗癫痫药、阿哌沙班和/或抗菌药的患者的用药时间:在一家单中心安全网医院对药剂师主导的干预措施进行了回顾性前期分析和后期分析。研究对象包括接受透析治疗并服用一种目标药物的患者。主要终点是漏服和延迟服药的综合结果:干预前组共有 25 名患者接受了 126 次透析治疗,干预后组共有 29 名患者接受了 80 次透析治疗。就主要终点而言,干预前组与干预后组分别有 118 例(18%)和 57 例(9.3%)患者漏服或延迟服药(P < 0.001)。干预后组中延迟用药的人数较少,从而达到了主要终点。干预后组中按正确时间表给药的抗菌药物数量有所增加(98.3% vs 99.1%,P = 0.044):由药剂师主导的对血液透析患者标准给药时间的干预增加了按时给药的处方药剂量。该干预措施还使更多的抗菌药物在相对于透析疗程的适当时间给药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of a Pharmacist-Led Implementation of Standardized Medication Administration Times for Inpatients Receiving Hemodialysis.

Background: Missed medication doses are a common and often preventable medication-related error that have been associated with an increased length of stay and mortality. Hemodialysis is a common, relatively predictable reason that patients are unavailable, resulting in missed doses.

Objective: To evaluate the implications of a pharmacist-led intervention to standardize the medication administration times for patients requiring hemodialysis who were prescribed antihypertensives, antiepileptics, apixaban, and/or antimicrobials.

Methods: A retrospective preanalysis and postanalysis of a pharmacist-led intervention were performed at a single-center, safety net hospital. Patients receiving dialysis and prescribed one of the targeted medications were included. The primary endpoint was the composite of missed and delayed doses.

Results: A total of 25 patients receiving 126 dialysis sessions in the preintervention group and 29 patients receiving 80 dialysis sessions in the postintervention group were included for analysis. For the primary endpoint, 118 (18%) versus 57 (9.3%) doses were missed or delayed in the preintervention versus postintervention group, respectively (P < 0.001). The primary endpoint was driven by fewer delayed doses in the postgroup. The number of antimicrobials given on a correct schedule increased in the postintervention group (98.3% vs 99.1%, P = 0.044).

Conclusion and relevance: A pharmacist-led intervention for standard medication administration times in patients requiring hemodialysis increased the number of prescribed medication doses given and given on time. The intervention also led to more antimicrobials administered at appropriate times relative to dialysis sessions.

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来源期刊
CiteScore
5.70
自引率
0.00%
发文量
166
审稿时长
3-8 weeks
期刊介绍: Annals of Pharmacotherapy (AOP) is a peer-reviewed journal that advances pharmacotherapy throughout the world by publishing high-quality research and review articles to achieve the most desired health outcomes.The articles provide cutting-edge information about the most efficient, safe and cost-effective pharmacotherapy for the treatment and prevention of various illnesses. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 14 days
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