脊柱手术中两种主要局部止血剂的比较评述

IF 0.2 Q4 ORTHOPEDICS
Ashish D. Chakraborty , Yixuan Tong , Charla Fischer
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引用次数: 0

摘要

在脊柱手术中实现充分止血对患者和外科医生来说都至关重要。目前,用于脊柱手术的局部止血基质剂主要有两种--Floseal(Baxter Healthcare,Deerfield,Illinois,USA)和 Surgiflo(Ethicon Inc.,Raritan,New Jersey,USA)。虽然这两种产品都被证明能有效止血,但在脊柱手术中使用哪种药剂优于另一种药剂还没有达成共识。有研究对 Floseal 和 Surgiflo 的疗效和成本进行了比较,但其中很大一部分研究都有行业背景。一般来说,现有文献报道使用其中一种药剂或另一种药剂可节省低至中等程度的成本,但在术后血肿等基于患者的结果方面并无明显的临床差异。动物模型研究也表明,使用可流动的局部止血剂会产生独特的并发症,包括硬膜外纤维化和相关的神经根压迫。有必要进一步开展非行业附属研究,以比较两种止血剂的疗效、患者预后、成本分析和可能出现的独特并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comparative Review of Two Major Topical Hemostasis Agents in Spine Surgery

Achieving adequate hemostasis in spine surgery is critical for both the patient and surgeon. Currently, there are 2 major topical hemostatic matrix agents used in spine surgery—Floseal (Baxter Healthcare, Deerfield, Illinois, USA) and Surgiflo (Ethicon Inc., Raritan, New Jersey, USA). While both products have been shown to be effective at achieving hemostasis, there is no consensus supporting the use of one agent over another in spine surgery. There are studies comparing outcomes and cost between Floseal and Surgiflo, but a significant portion of the studies have industry affiliations. Generally, existing literature reports low to moderate cost savings in favor of one agent or the other, with no clinically significant differences in patient-based outcomes such as postoperative hematomas. Animal model studies also suggest unique complications, including epidural fibrosis and associated nerve root compression with use of a flowable topical hemostatic agent. Further nonindustry-affiliated studies are warranted to compare efficacy, patient outcomes, cost analyses, and possible unique complications associated with the two hemostatic agents.

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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
40
审稿时长
83 days
期刊介绍: Operative Techniques in Orthopaedics is an innovative, richly illustrated resource that keeps practitioners informed of significant advances in all areas of surgical management. Each issue of this atlas-style journal explores a single topic, often offering alternate approaches to the same procedure. Its current, definitive information keeps readers in the forefront of their specialty.
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