2 型糖尿病患者急性脑中风的病程特点

O.M. Yasnii, D.V. Lebedynets, M. Trishchynska
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引用次数: 0

摘要

急性中风在发展中国家和发达国家都是一个重大的公共卫生问题,对个人、家庭和 社会都有不利影响。缺血性中风是一种发病率高、致残率高、死亡率高、复发率高的疾病。糖尿病是当今最严重、最常见的慢性疾病之一,可引起危及生命的并发症,导致残疾。在这些并发症中,最常见的是急性中风。糖尿病患者发生急性缺血性中风的风险是非糖尿病患者的 1.5-2 倍。高血糖会使中风复发的风险增加一倍,并增加缺血性中风后死亡或致残的风险。糖尿病导致急性中风的机制可能有几种,包括心脏栓塞(心房颤动)、内皮功能障碍、幼年动脉僵化增加、全身炎症和毛细血管基底膜增厚。通过改变生活方式或药物控制血糖水平,并改变其他相关风险因素(如高血压和血脂异常),是有效预防中风的关键步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Features of the course of acute cerebral stroke in patients with type 2 diabetes
Acute stroke is a major public health problem in both developing and developed countries and has detrimental effects on the individual, family, and societal levels. Ischemic stroke is a disease with significant prevalence, high disability, high mortality, and high recurrence rate. Diabetes mellitus is one of the most serious and most common chronic diseases today, causing life-threatening complications that lead to disability. Among these complications, one of the most common is acute stroke. People with diabetes are at a 1.5–2 times higher risk of acute ischemic stroke compared to people without this disease. Hyperglycemia doubles the risk of recurrent stroke and increases the risk of death or disability after ischemic stroke. There are several possible mechanisms by which diabetes leads to acute stroke, including cardiac embolism (atrial fibrillation), endothelial dysfunction, increased arterial stiffness at an early age, systemic inflammation and thickening of the capillary basement membrane. Controlling glucose levels through lifestyle changes or medications and modifying other associated risk factors (such as hypertension and dyslipidemia) are critical steps to the effective stroke prevention.
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