骨水泥骨发育不良的肉瘤变:一份病例报告

Sailendranath Biswas, A. Saha, Asish K. Das, Shreya Ganguly
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引用次数: 0

摘要

颌骨纤维骨发育不良(COD)是一类罕见的良性纤维骨疾病,而骨源性肉瘤(OS)则是一种预后不佳的恶性肿瘤。颌骨良性纤维骨病变的恶性转化并不常见,也鲜有报道。本文介绍了一名患者的临床放射学检查结果和组织病理学分析,该患者的病变位于颌骨的四个象限,曾在一所地区牙科学院的门诊部就诊。病变在两个月内发生了肉瘤变,组织病理学评估证实了这一结果。虽然花骨水泥骨发育不良是颌骨的一种良性病变,恶变倾向很低,但对有肿瘤易感综合征的患者应密切监测。为了更好地了解不慎发生的变化,还需要进一步的研究和分子研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sarcomatous transformation of florid cemento-osseous dysplasia: a case report
Florid cemento-osseous dysplasia (COD) represents a rare group of benign fibro-osseous disorders, while osteogenic sarcoma (OS) on the other hand, is a malignant tumour of ominous prognosis. The malignant transformation of a benign fibro-osseous lesion of the jaw is quite uncommon and has few reported cases. The clinico-radiological findings and histopathological analysis of a lesion present in all four quadrants of the jaw of a patient who reported at the outpatient department of a regional dental college is presented here. The lesion underwent sarcomatous transformation over two months and the findings were confirmed by histopathological evaluation. Although florid cemento-osseous dysplasia is a benign lesion of the jaw with a very low propensity for malignant transformation, it should be closely monitored in patients with tumour predisposition syndromes. Further research and molecular studies are required for better understanding of inadvertent changes.
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