脾脓肿,镰状细胞地中海贫血症病例中的罕见并发症

Ankitha Ponathil, Rajesh Rai, P. Inamdar, R. Naulakha
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摘要

镰状细胞病(SCD)是一种遗传性常染色体隐性血红蛋白病。镰状细胞β地中海贫血症是镰状细胞病的一种变异综合征,其特征是镰状细胞基因和β地中海贫血基因的复合杂合子。我们报告了一例 12 岁男童的病例,他在 2 岁时被诊断为镰状细胞地中海贫血,主诉为发烧、眼睛变黄和嗜睡。腹部 USG 检查提示脾脏肿大,脾脏实质内散布着多个界限不清、不均匀的低回声区,内无血管,可能为脾脏微脓肿。患儿开始接受抗生素治疗,包括厌氧菌和革兰氏阳性菌(万古霉素、美罗培南、阿米卡星和甲硝唑)。目前,患儿情况良好,症状大为缓解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Splenic abscess, a rare complication in a case of sickle cell thalassemia
Sickle cell disease (SCD) is an inherited autosomal recessive haemoglobinopathy. Sickle cell beta thalassemia is a variant syndrome of SCD characterised by the compound heterozygosity for sickle and beta thalassemia genes. We present a case of 12 year old male child diagnosed case of sickle cell thalassemia at the age of 2 years with complaints of fever, yellowish discolouration of eyes and drowsiness. USG abdomen was done suggestive of splenomegaly, multiple ill-defined, heterogeneously hypo-echoic, areas scattered throughout the splenic parenchyma with no vascularity within likely representing as splenic micro-abscesses. Child was started on antibiotics covering anaerobic and gram-positive organisms (vancomycin, meropenem, amikacin and metronidazole). Currently child is doing well with huge relieve to his symptoms.
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