新西兰医院老年住院病人样本中痴呆和谵妄与健康结果的关系

Cristian Gonzalez-Prieto, E. Groenewald, S. Yates, Bede Oulaghan, C. Rivera-Rodriguez, Daniel Wilson, Gillian Dobbie, Sarah Cullum
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摘要

痴呆和谵妄在老年住院病人中经常出现。多达三分之一的老年住院病人患有痴呆症,约三分之一的老年住院病人也会出现谵妄,通常与痴呆症同时存在。患有痴呆症和/或谵妄的患者,其健康状况(如死亡率、住院时间和出院后入住护理之家)可能会更差。以新西兰一家医院的病人为样本,描述痴呆和谵妄与健康结果(住院时间、死亡率、入住护理院)之间的关系。从2013年至2021年期间在新西兰一家记忆服务机构接受评估的2248名老年患者的连续样本中提取例行收集的数据,以研究谵妄和痴呆与患者健康结果(住院时间、入住护理院和死亡率)之间的关联。在接受评估的2248名患者中,75%在确诊后住院治疗,其中半数在医院接受了谵妄筛查。痴呆症患者出现谵妄的风险是普通人的三倍(OR=3.0,95% CI:2.0-4.6,p<0.001)。与新西兰籍欧洲人相比,太平洋岛国人仅患有痴呆症或谵妄叠加痴呆症的调整后相对风险比分别为2.3(p<0.001)和2.9(p<0.001)。与未被诊断出谵妄的患者相比,谵妄患者(无论是否患有痴呆症)的平均住院时间更长,被安置在护理院的可能性高出两到四倍,死亡风险高出1.7-3.1倍。谵妄在老年住院病人中非常常见,对病人的治疗效果和医疗费用有重大影响。太平洋岛屿族裔患痴呆症和谵妄症的风险似乎都更高,临床结果也更差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The association of dementia and delirium with health outcomes in a sample of older inpatients in a New Zealand hospital setting
Both dementia and delirium are seen frequently in older hospital inpatients. Dementia is present in up to one-third of older hospital inpatients, and delirium also occurs in around one-third of older inpatients, often alongside dementia. Patients’ health outcomes, such as mortality, length of stay, and discharge to a care home, may be worse in patients with dementia and/or delirium. To describe the association of dementia and delirium with health outcomes (length of stay, mortality, care home placement) in a sample of patients from a New Zealand hospital setting. Routinely collected data from a consecutive sample of 2248 older patients assessed in a New Zealand memory service from 2013 to 2021 were extracted to examine the associations of delirium and dementia with patients’ health outcomes: length of stay, care home placement, and mortality. Of the 2248 patients assessed, 75% were hospitalised after diagnosis, and half of these had delirium screening in hospital. People with dementia had three times the risk of experiencing delirium (OR=3.0, 95% CI:2.0-4.6, p<0.001). In Pacific people compared to NZ Europeans, the adjusted relative risk ratios for having dementia only or delirium superimposed on dementia, compared to those with neither, were 2.3 (p<0.001) and 2.9 (p<0.001), respectively. Compared to people with neither diagnosis, people with delirium (with or without dementia) had a longer mean length of stay, were two to four times more likely to be placed in a care home, and the risk of death was 1.7-3.1 times higher. Delirium is very common in older hospital inpatients and has a major impact on patient outcomes and health costs. Pacific peoples seem to have greater risk of both dementia and delirium, associated with worse clinical outcomes.
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