全股骨置换术的临床结果。拉丁美洲的首次经验

IF 2.3 4区 医学 Q3 ONCOLOGY
Jorge Cabrolier , Oscar Ceballos , Fabiola Rieloff , Francisco Hardoy , Ricardo Tolosa , Orlando Wevar
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引用次数: 0

摘要

导言:股骨经常受到原发性和转移性骨肿瘤的影响。在骨质大量流失的病例中,全股骨置换术(TFR)仍是唯一可行的保肢方案。本研究调查了拉丁美洲地区全股骨置换术患者的临床疗效,并进行了至少 3 年的随访。因肿瘤适应症或肿瘤相关手术引起的并发症而接受TFR手术的患者均被纳入其中。记录了手术适应症和术后并发症的相关数据。为了评估功能状态,采用了肌肉骨骼肿瘤协会(MSTS)评分和多伦多肢体救治评分(TESS)。诊断结果包括八例骨肉瘤、四例软骨肉瘤、一例尤文肉瘤和一例巨细胞瘤。10名患者之前接受过手术。在78.6%的病例中,TFR的诱因是之前手术的并发症。35.7%的患者在TFR术后出现并发症,需要再次手术。3年后,MSTS和TESS的平均得分分别为67.4%和70.8%。结论对于股骨严重缺损的肿瘤患者来说,全股骨置换术是一种非常有价值的肢体挽救方案,但存在很大的并发症风险。鉴于其潜在的益处,发展中国家必须考虑将全股骨置换术纳入其医疗体系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical outcomes of total femoral replacement. First Latin American experience

Introduction

The femur is frequently affected by primary and metastatic bone tumors. In cases with substantial bone loss, Total Femur Replacement (TFR) remains the only viable limb preservation option. This study investigates the clinical outcomes of TFR patients in a Latin American setting, with a minimum 3-year follow-up.

Methods

Retrospective review identifying cases of TFR at a single center from 2009 to 2020. Patients who had TFR either due to oncological indications or complications arising from oncology-related surgeries were included. Data on the indications for surgery and post-operative complications were recorded. To assess functional status, the Musculoskeletal Tumor Society (MSTS) score and the Toronto Extremity Salvage Score (TESS) were used.

Results

Fourteen patients met the inclusion criteria. Diagnoses included eight osteosarcomas, four chondrosarcomas, one Ewing sarcoma, and one giant cell tumor. Ten patients had undergone prior surgeries. Indication for TFR was a complication of a previous surgery in 78.6 % of cases. Post-TFR complications were experienced by 35.7 % of patients, requiring further surgeries. At the 3-year mark, average MSTS and TESS scores were 67.4 % and 70.8 %, respectively.

Conclusion

Total femur replacement serves as a valuable limb salvage solution for patients with significant femoral defects in oncological scenarios, however, there is a significant risk of complications. Given its potential benefits, it is essential for developing countries to consider incorporating TFR into their healthcare systems.

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来源期刊
Surgical Oncology-Oxford
Surgical Oncology-Oxford 医学-外科
CiteScore
4.50
自引率
0.00%
发文量
169
审稿时长
38 days
期刊介绍: Surgical Oncology is a peer reviewed journal publishing review articles that contribute to the advancement of knowledge in surgical oncology and related fields of interest. Articles represent a spectrum of current technology in oncology research as well as those concerning clinical trials, surgical technique, methods of investigation and patient evaluation. Surgical Oncology publishes comprehensive Reviews that examine individual topics in considerable detail, in addition to editorials and commentaries which focus on selected papers. The journal also publishes special issues which explore topics of interest to surgical oncologists in great detail - outlining recent advancements and providing readers with the most up to date information.
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