Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero
{"title":"意义未定的不典型性和 ThyroSeq v3 阳性调用率作为细胞学实验室绩效的质量控制指标","authors":"Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero","doi":"10.1101/2024.01.24.24301631","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.","PeriodicalId":501528,"journal":{"name":"medRxiv - Pathology","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Atypia of Undetermined Significance and ThyroSeq v3 Positive Call Rates as Quality Control Metrics for Cytology Laboratory Performance\",\"authors\":\"Odille Mejia-Mejia, Andres Bravo-Gonzalez, Monica Sanchez-Avila, Youley Tjendra, Rodrigo Santoscoy, Katherine Drews-Elger, Yiqin Zuo, Camilo Arias-Abad, Carmen Gomez, Monica Garcia-Buitrago, Mehrdad Nadji, Merce Jorda, Jaylou M. Velez-Torres, Roberto Ruiz-Cordero\",\"doi\":\"10.1101/2024.01.24.24301631\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.\",\"PeriodicalId\":501528,\"journal\":{\"name\":\"medRxiv - Pathology\",\"volume\":\"10 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.24.24301631\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.24.24301631","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景 用于报告甲状腺细胞病理学的贝塞斯达系统(TBS)建议 "意义未定的不典型性(AUS)"率为 10%。最近的数据表明,当分子检测结果呈阳性的病例比例较低时,这一类别可能会被过度使用。作为一项质量指标,我们计算了细胞学实验室和每位细胞病理学家的 AUS 和阳性呼叫率。
Atypia of Undetermined Significance and ThyroSeq v3 Positive Call Rates as Quality Control Metrics for Cytology Laboratory Performance
Background The Bethesda system (TBS) for reporting thyroid cytopathology recommends an “atypia of undetermined significance (AUS)” rate of 10%. Recent data suggest that this category might be overused when the rate of cases with molecular positive results is low. As a quality metric, we calculated the AUS and positive call rates for our cytology lab and each cytopathologist.