胰腺导管腺癌切除术后的监测:如何进行监测,有何益处?

IF 2.5 3区 医学 Q1 SURGERY
Scandinavian Journal of Surgery Pub Date : 2024-06-01 Epub Date: 2024-01-30 DOI:10.1177/14574969231156353
Roland Andersson, Daniel Ansari, Caj Haglund
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引用次数: 0

摘要

背景和目的:胰腺癌根治性切除术后的监测方法差别很大,支持性证据也很有限。复发虽然频繁,但至少在最初两年内不会复发。监测的成本可能很高,但有关监测如何影响总生存率的证据尚未完全阐明:方法、结果:有报告显示,生物学复发迹象(CA 19-9升高)比放射学显示的复发早几个月:结论:讨论了提前启动挽救治疗的可能性,这种可能性可能基于未来改进的生物标志物面板。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surveillance after resection of pancreatic ductal adenocarcinoma: How to do it and what are the benefits?

Background and objective: Surveillance following resection with curative intent of pancreatic cancer varies widely, and supporting evidence is limited. Recurrence is although frequent, not at least during the first 2 years. Surveillance may be costly, but evidence on how this influences overall survival is not fully elucidated.

Methods, results: There are reports implying that signs of biological recurrence (increasing CA 19-9) precede radiologically demonstrated recurrence by months.

Conclusions: The possibility of initiating salvage therapy earlier is discussed, potentially based on improved future biomarker panels.

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来源期刊
CiteScore
5.50
自引率
4.20%
发文量
37
审稿时长
6-12 weeks
期刊介绍: The Scandinavian Journal of Surgery (SJS) is the official peer reviewed journal of the Finnish Surgical Society and the Scandinavian Surgical Society. It publishes original and review articles from all surgical fields and specialties to reflect the interests of our diverse and international readership that consists of surgeons from all specialties and continents.
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