变性共济失调患者使用语音训练器应用程序控制发声:试点干预研究

IF 2.7 3区 医学 Q3 NEUROSCIENCES
Cerebellum Pub Date : 2024-08-01 Epub Date: 2024-01-29 DOI:10.1007/s12311-024-01662-5
S Knuijt, J Nonnekes, B P C van de Warrenburg, M Nijkamp, S Scholten, B J M de Swart, J G Kalf
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引用次数: 0

摘要

构音障碍是退行性共济失调患者的致残因素。语言治疗干预的证据有限。在这项试点研究中,我们使用了最初为帕金森病患者开发的语音训练器应用程序作为发声控制的反馈工具。我们假设,共济失调性构音障碍患者将受益于语音训练器应用程序,从而更好地控制自己的声音响度和音调,降低说话速度,提高清晰度。这项干预研究包括在 3 周内进行 5 次治疗,每次 30 分钟,采用音调限制嗓音治疗原则。在练习过程中,患者会收到关于响度和音高的实时视觉反馈。此外,我们还鼓励患者在家练习或在日常生活中使用嗓音训练器。我们采用了观察者评分和患者评分两种结果测量方法。主要结果指标是通过荷兰语句子可懂度测试得出的可懂度。25名退行性共济失调患者中有21人完成了治疗。我们发现,患者的语言理解能力在统计学上没有明显改善(p = .56)。但是,在干预后,患者说话的速度变慢了(p = .03),停顿的时间变长了(p = .05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Use of the Voice Trainer App for Vocal Control in People with a Degenerative Ataxia: A Pilot Intervention Study.

The Use of the Voice Trainer App for Vocal Control in People with a Degenerative Ataxia: A Pilot Intervention Study.

Dysarthria is disabling in persons with degenerative ataxia. There is limited evidence for speech therapy interventions. In this pilot study, we used the Voice trainer app, which was originally developed for patients with Parkinson's disease, as a feedback tool for vocal control. We hypothesized that patients with ataxic dysarthria would benefit from the Voice trainer app to better control their loudness and pitch, resulting in a lower speaking rate and better intelligibility. This intervention study consisted of five therapy sessions of 30 min within 3 weeks using the principles of the Pitch Limiting Voice Treatment. Patients received real-time visual feedback on loudness and pitch during the exercises. Besides, they were encouraged to practice at home or to use the Voice trainer in daily life. We used observer-rated and patient-rated outcome measures. The primary outcome measure was intelligibility, as measured by the Dutch sentence intelligibility test. Twenty-one out of 25 included patients with degenerative ataxia completed the therapy. We found no statistically significant improvements in intelligibility (p = .56). However, after the intervention, patients were speaking slower (p = .03) and the pause durations were longer (p < .001). The patients were satisfied about using the app. At the group level, we found no evidence for an effect of the Voice trainer app on intelligibility in degenerative ataxia. Because of the heterogeneity of ataxic dysarthria, a more tailor-made rather than generic intervention seems warranted.

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来源期刊
Cerebellum
Cerebellum 医学-神经科学
CiteScore
6.40
自引率
14.30%
发文量
150
审稿时长
4-8 weeks
期刊介绍: Official publication of the Society for Research on the Cerebellum devoted to genetics of cerebellar ataxias, role of cerebellum in motor control and cognitive function, and amid an ageing population, diseases associated with cerebellar dysfunction. The Cerebellum is a central source for the latest developments in fundamental neurosciences including molecular and cellular biology; behavioural neurosciences and neurochemistry; genetics; fundamental and clinical neurophysiology; neurology and neuropathology; cognition and neuroimaging. The Cerebellum benefits neuroscientists in molecular and cellular biology; neurophysiologists; researchers in neurotransmission; neurologists; radiologists; paediatricians; neuropsychologists; students of neurology and psychiatry and others.
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