改善心脏麻痹对心脏保护作用的新策略

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Estefanie Osorio-Llanes, Jairo Castellar-López, Wendy Rosales-Rada, Yulieth Montoya, John Bustamante, Ricardo Zalaquett, Roberto Bravo-Sagua, Jaime A Riquelme, Gina Sánchez, Mario Chiong, Sergio Lavandero, Evelyn Mendoza-Torres
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引用次数: 0

摘要

使用心脏保护策略作为心脏麻痹溶液的辅助剂已成为改善术后心脏恢复的理想选择。在心血管外科领域,最佳心脏保护剂的选择及其分配机制仍存在争议。在心脏麻痹手术过程中,仍然需要寻找新的、更好的心脏保护方法。随着新的替代品和添加剂的出现,在心脏麻痹期间处理心血管并发症的新技术也在不断发展,每一种新策略都为中和缺血/再灌注事件后的损伤提供了一种工具。研究人员和临床医生致力于研究新策略和辅助成分的效果,这些新策略和辅助成分有可能改善心脏麻痹溶液的心脏保护效果,防止心脏手术过程中心肌缺血/再灌注引起的损伤。本综述旨在探讨不同类型的心脏麻痹剂、它们的保护机制,以及有哪些策略被提出来增强这些溶液在暴露于心血管病变的心脏中的功能,这些病变需要外科手术来纠正。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel Strategies to Improve the Cardioprotective Effects of Cardioplegia.

The use of cardioprotective strategies as adjuvants of cardioplegic solutions has become an ideal alternative for the improvement of post-surgery heart recovery. The choice of the optimal cardioplegia, as well as its distribution mechanism, remains controversial in the field of cardiovascular surgery. There is still a need to search for new and better cardioprotective methods during cardioplegic procedures. New techniques for the management of cardiovascular complications during cardioplegia have evolved with new alternatives and additives, and each new strategy provides a tool to neutralize the damage after ischemia/reperfusion events. Researchers and clinicians have committed themselves to studying the effect of new strategies and adjuvant components with the potential to improve the cardioprotective effect of cardioplegic solutions in preventing myocardial ischemia/reperfusion-induced injury during cardiac surgery. The aim of this review is to explore the different types of cardioplegia, their protection mechanisms, and which strategies have been proposed to enhance the function of these solutions in hearts exposed to cardiovascular pathologies that require surgical alternatives for their corrective progression.

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来源期刊
Current Cardiology Reviews
Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.70
自引率
10.50%
发文量
117
期刊介绍: Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.
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