有月经症状的女性长COVID患者的临床特征：一项来自日本门诊的回顾性研究。

IF 2.1 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Psychosomatic Obstetrics & Gynecology Pub Date : 2024-12-01 Epub Date: 2024-01-25 DOI:10.1080/0167482X.2024.2305899

Yasue Sakurada, Yui Matsuda, Kanon Motohashi, Toru Hasegawa, Yuki Otsuka, Yasuhiro Nakano, Kazuki Tokumasu, Koichiro Yamamoto, Naruhiko Sunada, Hiroyuki Honda, Hideharu Hagiya, Keigo Ueda, Fumio Otsuka

{"title":"有月经症状的女性长COVID患者的临床特征：一项来自日本门诊的回顾性研究。","authors":"Yasue Sakurada, Yui Matsuda, Kanon Motohashi, Toru Hasegawa, Yuki Otsuka, Yasuhiro Nakano, Kazuki Tokumasu, Koichiro Yamamoto, Naruhiko Sunada, Hiroyuki Honda, Hideharu Hagiya, Keigo Ueda, Fumio Otsuka","doi":"10.1080/0167482X.2024.2305899","DOIUrl":null,"url":null,"abstract":"Purpose: To elucidate the impact of long COVID on menstruation and mental health, medical records of patients with long COVID were evaluated.Methods: Symptoms of long COVID, QOL, mental health, and related endocrine data were compared between two groups with and without menstrual disturbances.Results: Of 349 female patients who visited our clinic between February 2021 and March 2023, 223 patients with long COVID (aged 18-50 years) were included. Forty-four (19.7%) of the patients had menstrual symptoms associated with long COVID. The patients with menstrual symptoms were older than those without menstrual symptoms (42.5 vs. 38 years). The percentage of patients with menstrual symptoms was higher during the Omicron phase (24%) than during the Preceding (13%) and Delta (12%) phases. Cycle irregularity was the most frequent (in 63.6% of the patients), followed by severe pain (25%), heavy bleeding (20.5%), perimenopausal symptoms (18.2%), and premenstrual syndrome (15.9%). Fatigue and depression were the most frequent complications. Scores for fatigue and for QOL were significantly worse in long COVID patients with menstrual symptoms. Results of endocrine examinations showed significantly increased cortisol levels in patients with menstrual complaints.Conclusion: Long COVID has an impact on menstrual conditions and on QOL related to menstrual conditions.","PeriodicalId":50072,"journal":{"name":"Journal of Psychosomatic Obstetrics & Gynecology","volume":"45 1","pages":"2305899"},"PeriodicalIF":2.1000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical characteristics of female long COVID patients with menstrual symptoms: a retrospective study from a Japanese outpatient clinic.\",\"authors\":\"Yasue Sakurada, Yui Matsuda, Kanon Motohashi, Toru Hasegawa, Yuki Otsuka, Yasuhiro Nakano, Kazuki Tokumasu, Koichiro Yamamoto, Naruhiko Sunada, Hiroyuki Honda, Hideharu Hagiya, Keigo Ueda, Fumio Otsuka\",\"doi\":\"10.1080/0167482X.2024.2305899\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: To elucidate the impact of long COVID on menstruation and mental health, medical records of patients with long COVID were evaluated.Methods: Symptoms of long COVID, QOL, mental health, and related endocrine data were compared between two groups with and without menstrual disturbances.Results: Of 349 female patients who visited our clinic between February 2021 and March 2023, 223 patients with long COVID (aged 18-50 years) were included. Forty-four (19.7%) of the patients had menstrual symptoms associated with long COVID. The patients with menstrual symptoms were older than those without menstrual symptoms (42.5 vs. 38 years). The percentage of patients with menstrual symptoms was higher during the Omicron phase (24%) than during the Preceding (13%) and Delta (12%) phases. Cycle irregularity was the most frequent (in 63.6% of the patients), followed by severe pain (25%), heavy bleeding (20.5%), perimenopausal symptoms (18.2%), and premenstrual syndrome (15.9%). Fatigue and depression were the most frequent complications. Scores for fatigue and for QOL were significantly worse in long COVID patients with menstrual symptoms. Results of endocrine examinations showed significantly increased cortisol levels in patients with menstrual complaints.Conclusion: Long COVID has an impact on menstrual conditions and on QOL related to menstrual conditions.\",\"PeriodicalId\":50072,\"journal\":{\"name\":\"Journal of Psychosomatic Obstetrics & Gynecology\",\"volume\":\"45 1\",\"pages\":\"2305899\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Psychosomatic Obstetrics & Gynecology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/0167482X.2024.2305899\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psychosomatic Obstetrics & Gynecology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/0167482X.2024.2305899","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的：为了阐明长期月经失调对月经和心理健康的影响，我们对长期月经失调患者的病历进行了评估：方法：比较有月经紊乱和无月经紊乱两组患者的长期COVID症状、QOL、心理健康和相关内分泌数据：结果：在 2021 年 2 月至 2023 年 3 月期间就诊的 349 名女性患者中，有 223 名患者患有长 COVID（18-50 岁）。其中 44 名患者（19.7%）有与长 COVID 相关的月经症状。有月经症状的患者年龄比无月经症状的患者大（42.5 岁对 38 岁）。有月经症状的患者在 Omicron 期（24%）的比例高于 Preceding 期（13%）和 Delta 期（12%）。最常见的症状是月经周期不规律（占 63.6%），其次是剧烈疼痛（25%）、大量出血（20.5%）、围绝经期症状（18.2%）和经前综合征（15.9%）。疲劳和抑郁是最常见的并发症。有月经症状的长期 COVID 患者的疲劳和 QOL 评分明显较差。内分泌检查结果显示，月经不调患者的皮质醇水平明显升高：结论：长期 COVID 会影响月经状况以及与月经状况相关的 QOL。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clinical characteristics of female long COVID patients with menstrual symptoms: a retrospective study from a Japanese outpatient clinic.

Purpose: To elucidate the impact of long COVID on menstruation and mental health, medical records of patients with long COVID were evaluated.

Methods: Symptoms of long COVID, QOL, mental health, and related endocrine data were compared between two groups with and without menstrual disturbances.

Results: Of 349 female patients who visited our clinic between February 2021 and March 2023, 223 patients with long COVID (aged 18-50 years) were included. Forty-four (19.7%) of the patients had menstrual symptoms associated with long COVID. The patients with menstrual symptoms were older than those without menstrual symptoms (42.5 vs. 38 years). The percentage of patients with menstrual symptoms was higher during the Omicron phase (24%) than during the Preceding (13%) and Delta (12%) phases. Cycle irregularity was the most frequent (in 63.6% of the patients), followed by severe pain (25%), heavy bleeding (20.5%), perimenopausal symptoms (18.2%), and premenstrual syndrome (15.9%). Fatigue and depression were the most frequent complications. Scores for fatigue and for QOL were significantly worse in long COVID patients with menstrual symptoms. Results of endocrine examinations showed significantly increased cortisol levels in patients with menstrual complaints.

Conclusion: Long COVID has an impact on menstrual conditions and on QOL related to menstrual conditions.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Psychosomatic Obstetrics & Gynecology 医学-妇产科学

CiteScore

6.10

自引率

3.20%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Psychosomatic Obstetrics and Gynecology was founded in 1982 in order to provide a scientific forum for obstetricians, gynecologists, psychiatrists and psychologists, academic health professionals as well as for all those who are interested in the psychosocial and psychosomatic aspects of women’s health. Another of its aims is to stimulate obstetricians and gynecologists to pay more attention to this very important facet of their profession.