西葫芦花提取物对雄性大鼠肾毒性的治疗作用

D. A. Zaki, A. Abdel-Ghany
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引用次数: 0

摘要

:西葫芦(Cucurbita pepo L.)花被视为农业废弃物。尽管它含有大量不同的营养成分和生物活性成分。但关于西葫芦花可能带来的营养和健康益处的信息并不多。因此,本次调查研究的目的是确定西葫芦花提取物(ZFE)对治疗肾损伤高尿酸血症大鼠的疗效。同时研究西葫芦花提取物作为抗癌药物对肝脏和肾脏的影响。本研究将 24 只雄性白化大鼠分为四组(n = 6)。第一组为阴性对照组,只接受基本饮食。其余 18 只大鼠(n = 18)在摄入基本食物的同时,连续 7 天注射庆大霉素(100 毫克/千克体重/天)以引起高尿酸血症,从而导致肾损伤。高尿酸血症大鼠随后被分成三组:第一组为阳性对照组,不接受任何治疗,第二组为阴性对照组,不接受任何治疗,第三组为阳性对照组,不接受任何治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Curative effect of zucchini flower extract on renal toxicity in male rats
: Zucchini ( Cucurbita pepo L.) flowers considered as agriculture wastes. Even though its contain high different quantities of nutrients and bioactive components. There isn't much information on the possible nutritional and healthy benefits of zucchini flowers. So, the aim of the current investigation study was to determine zucchini flower extract (ZFE) might had the curative effect of treating renal injured hyperuricemic rats. As well as studying the impact of ZFE on liver and kidney as anticancer. 24 male albino rats were divided into four groups (n = 6) for this study. The first group functioned as the negative control and just received a basic diet. The remaining rats (n = 18) were given a basic diet and injected with gentamicin (100 mg/kg BW/day) for 7 days to cause hyperuricemia, which results in kidney injury. The hyperuricemic rats were subsequently split into three groups; the first group acted as the positive control and did not get any therapy, while the second
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