异翅类：治疗蛋白质的宝库

IF 4.7 3区农林科学 Q1 ENTOMOLOGY

Journal of Insects as Food and Feed Pub Date : 2024-01-10 DOI:10.1163/23524588-00001062

M.R. Devi, A.S. Koijam, A. Brockmann, Y. Rajashekar

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引用次数: 0

摘要

杂翅目昆虫属于高度多样化的昆虫群体，包括陆生或水生昆虫，有以植物为食的昆虫、以血液为食的昆虫、捕食昆虫、食腐昆虫、食腐昆虫和食菌昆虫。这些昆虫被用于昆虫食疗和昆虫治疗。食用昆虫是重要的生物活性次生代谢物和生物活性肽的来源，具有治疗代谢紊乱的营养保健潜力。据报道，来自异翅昆虫的各种毒肽具有治疗特性，目前正在对其治疗各种疾病的效果进行持续研究。本综述列举了可食用的异翅目昆虫以及从异翅目昆虫中鉴定出的可用作替代药物的生物活性肽。文中简要介绍了异翅目昆虫的种类和食性。讨论了生物信息学在昆虫毒液转化方面的作用。此外，还讨论了基于治疗功能的蛋白质和肽的可能探索，以及使用现代生物信息学工具和科学验证过程进行高级研究的必要性。

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Heteropterans: a treasure trove of therapeutic proteins

Heteroptera belongs to a group of highly diversified insect forms ranging from plant feeders, blood-feeders, predators, scavengers, detritivores, and fungivores with terrestrial or aquatic habitats. These insects have been used in entomophagy and entomotherapeutic practices. Edible insects are a source of essential bioactive secondary metabolites and bioactive peptides, having nutraceutical potential to deal with metabolic disorders. Various venomous peptides from heteropterans with therapeutic properties have been reported and are constantly being investigated for various medical conditions. This review enlists heteropteran edible insects and bioactive peptides identified from heteropterans for use as an alternative medicine. The heteropteran categories and feeding habits have been briefly outlined. The role of bioinformatics in putting up a translational aspect of insect venom has been discussed. Further, the possible exploration of therapeutic function-based proteins and peptides and the need for advanced studies using modern bioinformatics tools, and scientific validation processes are also discussed.

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来源期刊

Journal of Insects as Food and Feed Agricultural and Biological Sciences-Insect Science

CiteScore

7.00

自引率

17.60%

发文量

133

期刊介绍： The Journal of Insects as Food and Feed covers edible insects from harvesting in the wild through to industrial scale production. It publishes contributions to understanding the ecology and biology of edible insects and the factors that determine their abundance, the importance of food insects in people’s livelihoods, the value of ethno-entomological knowledge, and the role of technology transfer to assist people to utilise traditional knowledge to improve the value of insect foods in their lives. The journal aims to cover the whole chain of insect collecting or rearing to marketing edible insect products, including the development of sustainable technology, such as automation processes at affordable costs, detection, identification and mitigating of microbial contaminants, development of protocols for quality control, processing methodologies and how they affect digestibility and nutritional composition of insects, and the potential of insects to transform low value organic wastes into high protein products. At the end of the edible insect food or feed chain, marketing issues, consumer acceptance, regulation and legislation pose new research challenges. Food safety and legislation are intimately related. Consumer attitude is strongly dependent on the perceived safety. Microbial safety, toxicity due to chemical contaminants, and allergies are important issues in safety of insects as food and feed. Innovative contributions that address the multitude of aspects relevant for the utilisation of insects in increasing food and feed quality, safety and security are welcomed.