益生菌及其在癌症治疗中的作用综述

Rajshree Dahiya, Sumayya Khan, Sanket Kumar
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引用次数: 0

摘要

益生菌是一种有益细菌,摄入后可为人体健康带来诸多益处,并有助于保持肠道微生物群的平衡。这些有益菌存在于食物、保健品和药品中。含有益生菌的食品包括酸奶、豆豉和味噌,而乳酸菌和双歧杆菌是各种应用中常用的主要微生物菌株。由于益生菌对健康的潜在益处和最小的副作用,益生菌被全球广泛接受。保持肠道微生物群平衡对整体健康至关重要,肠道微生物群的任何紊乱都可能引发炎症免疫反应,引发癌症等各种疾病。癌症是一种严重且经常致命的疾病,影响着许多人。癌症是由于不受控制的细胞生长引起的,通常在晚期才被诊断出来。这种疾病起源于单个细胞,并有可能转移,在体内扩散。到目前为止,癌症还没有已知的治愈方法,而用于治疗癌症的传统化疗和合成药物的安全性和有效性也受到了严格的审查。这些疗法会对病人的健康产生负面影响,影响抗药性,而且往往过于昂贵,许多病人负担不起。因此,研究人员正在探索更有效、更安全的癌症治疗方法。某些益生菌株有可能通过改变肠道微生物群和改善人体防御系统的反应来预防癌症或作为传统化疗的补充。因此,本综述研究了益生菌作为预防和治疗癌症的替代方法的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Review on Probiotics and Their Role in the Management of Cancer
Probiotics are advantageous bacteria that provide numerous health benefits to individuals when ingested and help to keep the gut microbiota balance. These beneficial bacteria can be found in food, supplements, and medicines. Foods that contain probiotics include yogurt, tempeh, and miso, while bacteria of lactic acid and bifido are the predominant microbial strains commonly employed in various applications. Due to their potential health benefits and minimal side effects, probiotics are widely accepted globally. Maintaining a balanced gut microbiome is crucial for overall health, and any disturbance in the gut's microbiota can trigger inflammatory immune responses and initiate various diseases such as cancer. Cancer is a grave and frequently fatal illness that impacts a significant number of individuals. It arises due to uncontrolled cell growth and is usually diagnosed at an advanced stage. The disease originates from a single cell and can potentially metastasize, spreading through the body. As of now, cancer has no known cure, and the safety and efficacy of conventional chemotherapies and synthetic drugs employed in its treatment are subject to scrutiny. These treatments can negatively impact a patient's well-being, affect drug resistance, and are often too expensive for many patients to afford. Therefore, researchers are exploring more effective and safe ways to manage cancer. Certain probiotic strains have the potential to be beneficial in preventing cancer or as a complement to traditional chemotherapy by altering gut microbiota and improving the reactions of the body’s defense system. Hence, the review examines the likelihood of probiotics as simply an alternative approach to preventing and treating cancer.
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