Mukesh Kumar Saphi, Yalla Sai Vijaya Durga, Sunny Kumar Yadav, Krishnadev Shah, Amit Kumar
{"title":"普卢默-文森综合征:罕见病例报告","authors":"Mukesh Kumar Saphi, Yalla Sai Vijaya Durga, Sunny Kumar Yadav, Krishnadev Shah, Amit Kumar","doi":"10.61427/jcpr.v4.i1.2024.115","DOIUrl":null,"url":null,"abstract":"Plummer-Vinson syndrome, also called Paterson-Kelly syndrome, is characterized by the classic triad of dysphagia, iron-deficiency anemia, and esophageal webs. This syndrome is associated with an increased incidence of post-cricoid carcinoma and for surveillance, an endoscopy is recommended under general anesthesia. This was a case of 74-year-old woman with Plummer-Vinson Syndrome who was successfully treated with Savary-Gilliard (SG) dilation or Esophageal dilation. The patient had a long-standing clinical history of iron deficiency anemia with slow progression of dysphagia of solid food from 10 years and glossoepiglotic fold, aryepiglottic fold bilaterally arytenoid on the left & right side and had experienced difficulty in swallowing for the past 10 years. Along with this patient is having abdominal pain radiating to the epigastrium region and fever with chills & rigors. An endoscopy examination was conducted under general anesthesia and revealed the esophageal web at the level of the cervical esophagus. Laboratory data investigation shows an RBC count of 2.09 million/cumm, haemoglobin of 6.6 gm/dl%, and serum iron of 7µg/dl. The patient was prescribed Inj. Orofer-XT 100 mg intravenous iron sucrose supplement daily for 15 days, Inj. Pantoprazole 40 mg daily for 1 week, Inj. Tramadol 1amp whenever required and Syp.Sucralfate 15 ml 30 minutes before food. Her anemia condition was improved but dysphagia did not improve. To treat dysphagia the Savary-Gilliard (SG) dilation was done under fluoroscopy by endoscopically a single session was performed that serially increased the diameter by disrupting the web without any complication. After SG-dilation, the patient's dysphagia resolved shortly after the treatment.","PeriodicalId":513179,"journal":{"name":"Journal of Clinical and Pharmaceutical Research","volume":"20 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Plummer-Vinson Syndrome: A Rare Case Report\",\"authors\":\"Mukesh Kumar Saphi, Yalla Sai Vijaya Durga, Sunny Kumar Yadav, Krishnadev Shah, Amit Kumar\",\"doi\":\"10.61427/jcpr.v4.i1.2024.115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Plummer-Vinson syndrome, also called Paterson-Kelly syndrome, is characterized by the classic triad of dysphagia, iron-deficiency anemia, and esophageal webs. This syndrome is associated with an increased incidence of post-cricoid carcinoma and for surveillance, an endoscopy is recommended under general anesthesia. This was a case of 74-year-old woman with Plummer-Vinson Syndrome who was successfully treated with Savary-Gilliard (SG) dilation or Esophageal dilation. The patient had a long-standing clinical history of iron deficiency anemia with slow progression of dysphagia of solid food from 10 years and glossoepiglotic fold, aryepiglottic fold bilaterally arytenoid on the left & right side and had experienced difficulty in swallowing for the past 10 years. Along with this patient is having abdominal pain radiating to the epigastrium region and fever with chills & rigors. An endoscopy examination was conducted under general anesthesia and revealed the esophageal web at the level of the cervical esophagus. Laboratory data investigation shows an RBC count of 2.09 million/cumm, haemoglobin of 6.6 gm/dl%, and serum iron of 7µg/dl. The patient was prescribed Inj. Orofer-XT 100 mg intravenous iron sucrose supplement daily for 15 days, Inj. Pantoprazole 40 mg daily for 1 week, Inj. Tramadol 1amp whenever required and Syp.Sucralfate 15 ml 30 minutes before food. Her anemia condition was improved but dysphagia did not improve. To treat dysphagia the Savary-Gilliard (SG) dilation was done under fluoroscopy by endoscopically a single session was performed that serially increased the diameter by disrupting the web without any complication. After SG-dilation, the patient's dysphagia resolved shortly after the treatment.\",\"PeriodicalId\":513179,\"journal\":{\"name\":\"Journal of Clinical and Pharmaceutical Research\",\"volume\":\"20 8\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical and Pharmaceutical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.61427/jcpr.v4.i1.2024.115\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical and Pharmaceutical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.61427/jcpr.v4.i1.2024.115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Plummer-Vinson syndrome, also called Paterson-Kelly syndrome, is characterized by the classic triad of dysphagia, iron-deficiency anemia, and esophageal webs. This syndrome is associated with an increased incidence of post-cricoid carcinoma and for surveillance, an endoscopy is recommended under general anesthesia. This was a case of 74-year-old woman with Plummer-Vinson Syndrome who was successfully treated with Savary-Gilliard (SG) dilation or Esophageal dilation. The patient had a long-standing clinical history of iron deficiency anemia with slow progression of dysphagia of solid food from 10 years and glossoepiglotic fold, aryepiglottic fold bilaterally arytenoid on the left & right side and had experienced difficulty in swallowing for the past 10 years. Along with this patient is having abdominal pain radiating to the epigastrium region and fever with chills & rigors. An endoscopy examination was conducted under general anesthesia and revealed the esophageal web at the level of the cervical esophagus. Laboratory data investigation shows an RBC count of 2.09 million/cumm, haemoglobin of 6.6 gm/dl%, and serum iron of 7µg/dl. The patient was prescribed Inj. Orofer-XT 100 mg intravenous iron sucrose supplement daily for 15 days, Inj. Pantoprazole 40 mg daily for 1 week, Inj. Tramadol 1amp whenever required and Syp.Sucralfate 15 ml 30 minutes before food. Her anemia condition was improved but dysphagia did not improve. To treat dysphagia the Savary-Gilliard (SG) dilation was done under fluoroscopy by endoscopically a single session was performed that serially increased the diameter by disrupting the web without any complication. After SG-dilation, the patient's dysphagia resolved shortly after the treatment.